Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | GSK3A | P49840 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11332855 | 0.68 | CYP3A4 (0.51) | KDM4EGSK3AGSK3BCYP2C19TDP1 | |
| SCHEMBL719034 | 0.67 | NR4A2 (0.85) | KDM4EGSK3BCYP2C19TDP1MAPT | |
| SCHEMBL30121738 | 0.67 | NR4A2 (0.85) | KDM4EGSK3BCYP2C19TDP1MAPT | |
| SCHEMBL79657 | 0.65 | TDP1 (0.67) | KDM4EGSK3BCYP2C19TDP1MAPT | |
| SCHEMBL27719889 | 0.64 | TDP1 (0.64) | KDM4EGSK3BCYP2C19TDP1MAPT | |
| SCHEMBL7068671 | 0.63 | TDP1 (0.95) | KDM4EGSK3BCYP2C19TDP1MAPT | |
| SCHEMBL1052631 | 0.63 | TDP1 (0.86) | KDM4EGSK3BCYP2C19TDP1MAPT | |
| SCHEMBL4731087 | 0.63 | KDM4E (0.77) | KDM4EPKMCYP2C19MAPTLMNA | |
| SCHEMBL94886 | 0.62 | TDP1 (0.75) | KDM4EGSK3BCYP2C19TDP1MAPT | |
| SCHEMBL8519287 | 0.61 | TDP1 (1.00) | KDM4ECYP2C19TDP1MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4273873-A | BONDING SYNTHETIC FIBRINOLYTIC COMPOUND OR ENZYME | UNITIKA LTD. (JP) | 1981-06-16 | — | — | US | disclosed |