Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPSE | Q9Y251 | 4/20 | 0.47 |
| ▸ | SNCA | P37840 | 2/20 | 0.41 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.41 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.41 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.41 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | TIMP3 | P35625 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.38 |
| ▸ | ENTPD3 | O75355 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | TDP2 | O95551 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11341770 | 0.96 | HPSE (0.49) | HPSESNCATNNI3TNNT2TNNC1 | |
| SCHEMBL11346496 | 0.92 | HPSE (0.47) | HPSESNCATNNI3TNNT2TNNC1 | |
| SCHEMBL11343432 | 0.89 | HPSE (0.45) | HPSESNCATNNI3TNNT2TNNC1 | |
| SCHEMBL11338799 | 0.89 | SNCA (0.47) | HPSESNCATNNI3TNNT2TNNC1 | |
| SCHEMBL11348600 | 0.88 | SNCA (0.51) | HPSESNCATNNI3TNNT2TNNC1 | |
| SCHEMBL11339238 | 0.84 | HPSE (0.41) | HPSESNCATNNI3TNNT2TNNC1 | |
| SCHEMBL11341048 | 0.84 | MAPK14 (0.43) | HPSESNCATIMP3MEN1KMT2A | |
| SCHEMBL10823469 | 0.83 | HPSE (0.46) | HPSESNCATNNI3TNNT2TNNC1 | |
| SCHEMBL11338934 | 0.83 | TNNI3 (0.54) | HPSESNCATNNI3TNNT2TNNC1 | |
| SCHEMBL11342047 | 0.82 | HPSE (0.46) | HPSESNCAAURKBAURKATIMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4297372-A | ANTIARTHRITIC AGENTS; COLLAGENASE AND PROTEOLYTIC ENZYME INHIBITORS; BONE, SKIN, AND ORAL DISORDERS | AMERICAN CYANAMID COMPANY (US) | 1981-10-27 | — | — | US | disclosed |
| US-4216164-A | Ureide inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1980-08-05 | — | — | US | disclosed |