Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT2 | P31751 | 1/20 | 0.56 |
| ▸ | CLK2 | P49760 | 1/20 | 0.56 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.56 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.56 |
| ▸ | AURKA | O14965 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3831898 | 0.91 | AKT2 (0.51) | AKT2CLK2DYRK1ACLK4AURKA | |
| SCHEMBL15396404 | 0.90 | MEN1 (0.55) | AKT2CLK2DYRK1ACLK4AURKA | |
| SCHEMBL22191299 | 0.89 | AKT2 (0.52) | AKT2CLK2DYRK1ACLK4AURKA | |
| SCHEMBL11351869 | 0.87 | AKT2 (0.51) | AKT2CLK2DYRK1ACLK4AURKA | |
| SCHEMBL11356816 | 0.87 | ATM (0.52) | AKT2CLK2DYRK1ACLK4HSD17B10 | |
| SCHEMBL9994946 | 0.83 | HTT (0.56) | AURKAOPRM1KMT2AMEN1L3MBTL1 | |
| SCHEMBL22191531 | 0.80 | MAOB (0.44) | AKT2CLK2DYRK1ACLK4AURKA | |
| SCHEMBL22191252 | 0.79 | AKT2 (0.47) | AKT2CLK2DYRK1ACLK4AURKA | |
| SCHEMBL3010228 | 0.78 | MAPT (0.50) | AKT2CLK2DYRK1ACLK4AURKA | |
| SCHEMBL15396849 | 0.77 | MEN1 (0.68) | AURKAHSD17B10OPRM1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4275215-A | QUATERNARY AMMONIUM OR PHOSPHONIUM SALTS CATALYZE REACTION OF HYPOHALITE AND A DIPHENYL UREA | DOW CHEMICAL COMPANY LIMITED (GB) | 1981-06-23 | — | — | US | disclosed |