SCHEMBL11344121

SCHEMBL11344121

N/C(=C/c1ccc(O)cc1O)C/C(N)=C\c1ccc(O)cc1O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 3/20 0.44
SYNJ2 O15056 1/20 0.44
TTR P02766 1/20 0.44
CYP1A1 P04798 1/20 0.44
BCHE P06276 1/20 0.44
MMP2 P08253 1/20 0.44
ALOX5 P09917 1/20 0.44
PTPN1 P18031 1/20 0.44
PTGS1 P23219 1/20 0.44
CYP1B1 Q16678 1/20 0.44
PTPN22 Q9Y2R2 1/20 0.44
BACE1 P56817 1/20 0.44
MEN1 O00255 1/20 0.43
ALPL P05186 1/20 0.43
POLB P06746 1/20 0.43
ALPI P09923 1/20 0.43
ALPG P10696 1/20 0.43
KMT2A Q03164 1/20 0.43
EIF4H Q15056 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11344126 1.00 TYR (0.44) TYRSYNJ2TTRCYP1A1BCHE
SCHEMBL11334104 0.81 TYR (0.48) TYRSYNJ2TTRCYP1A1BCHE
SCHEMBL11334099 0.81 TYR (0.48) TYRSYNJ2TTRCYP1A1BCHE
SCHEMBL30058288 0.75 TRIM24 (0.46) MEN1POLBKMT2AL3MBTL1KDM4E
SCHEMBL11359639 0.72 TYR (0.48) TYRSYNJ2TTRCYP1A1BCHE
SCHEMBL1822010 0.71 TYR (0.75) TYRSYNJ2TTRCYP1A1BCHE
SCHEMBL1822012 0.71 TYR (0.75) TYRSYNJ2TTRCYP1A1BCHE
SCHEMBL11127568 0.69 BACE1 (0.39) TYRSYNJ2TTRCYP1A1BCHE
SCHEMBL29492373 0.68 EGFR (0.54) TYRSYNJ2TTRCYP1A1BCHE
Ethylenediamine SCHEMBL28556230 0.68 TYR (0.52) TYRSYNJ2TTRCYP1A1BCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4271251-A LEUCO DYE, PHOTOOXIDIZER, 2,4-DIHYDROXY-BENZALDOXIME FUJI PHOTO FILM CO., LTD. (JP) 1981-06-02 US disclosed
US-4066459-A IMINE COMPOUNDS HORIZONS INCORPORATED, A DIVISION OF HORIZONS RESEARCH INCORPORATED (US) 1978-01-03 US disclosed