Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.42 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.39 |
| ▸ | HTR3B | O95264 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.39 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.39 |
| ▸ | MIF | P14174 | 1/20 | 0.39 |
| ▸ | IGF1R | P08069 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | PPARA | Q07869 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15142215 | 0.81 | CYP1A2 (0.42) | TAAR1IGF1RALOX15MAOBIDO1 | |
| SCHEMBL31752269 | 0.81 | TAAR1 (0.42) | TAAR1MAOBPYCR1 | |
| SCHEMBL817399 | 0.80 | ANPEP (0.43) | SLC6A4 | |
| SCHEMBL817464 | 0.80 | ANPEP (0.43) | SLC6A4 | |
| SCHEMBL20488218 | 0.80 | SLC6A4 (0.48) | TAAR1PPARGPPARAIDO1PYCR1 | |
| SCHEMBL11062642 | 0.77 | TAAR1 (0.50) | TAAR1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL11340747 | 0.77 | HTT (0.49) | TAAR1MAOB | |
| SCHEMBL10585881 | 0.74 | TAAR1 (0.47) | TAAR1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL4070796 | 0.74 | TAAR1 (0.52) | TAAR1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL11052107 | 0.73 | STAT3 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4297516-A | PROSTAGLANDINS | AMERICAN CYANAMID COMPANY (US) | 1981-10-27 | — | — | US | disclosed |
| US-4235797-A | CHEMICAL INTERMEDIATES FOR PROSTAGLANDINS | AMERICAN CYANAMID COMPANY (US) | 1980-11-25 | — | — | US | disclosed |
| US-4212969-A | PROSTAGLANDINS | AMERICAN CYANAMID COMPANY (US) | 1980-07-15 | — | — | US | disclosed |
| US-4197245-A | 1-Hydroxymethyl-1-oxo-prostane derivatives of the A1 series | AMERICAN CYANAMID COMPANY (US) | 1980-04-08 | — | — | US | disclosed |
| US-4189597-A | PROSTAGLANDINS, BRONCHODILATORS | AMERICAN CYANAMID COMPANY (US) | 1980-02-19 | — | — | US | disclosed |
| US-4172839-A | PROSTAGLANDINS | AMERICAN CYANAMID COMPANY (US) | 1979-10-30 | — | — | US | disclosed |
| US-4170597-A | 1-Hydroxymethyl-1-oxo-prostane derivatives of the E2 series | AMERICAN CYANAMID COMPANY (US) | 1979-10-09 | — | — | US | disclosed |
| US-4154954-A | BRONCHODILATOR AGENTS; ANTIINFLAMMATORY AGENTS | AMERICAN CYANAMID COMPANY (US) | 1979-05-15 | — | — | US | disclosed |
| US-4085272-A | BRONCHODILATORS, INFLAMMATORY MEDEATOR RELEASE INHIBITORS | AMERICAN CYANAMID COMPANY (US) | 1978-04-18 | — | — | US | disclosed |