Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 2/20 | 0.56 |
| ▸ | CA1 | P00915 | 9/20 | 0.53 |
| ▸ | CA2 | P00918 | 9/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | HTR6 | P50406 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MMP1 | P03956 | 2/20 | 0.47 |
| ▸ | MMP2 | P08253 | 2/20 | 0.47 |
| ▸ | MMP9 | P14780 | 2/20 | 0.47 |
| ▸ | MMP8 | P22894 | 2/20 | 0.47 |
| ▸ | MMP13 | P45452 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 5/20 | 0.46 |
| ▸ | CA12 | O43570 | 4/20 | 0.46 |
| ▸ | CA4 | P22748 | 2/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.46 |
| ▸ | CA3 | P07451 | 1/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7263474 | 0.92 | CA1 (0.59) | KEAP1CA1CA2KMT2AHTR6 | |
| SCHEMBL8564462 | 0.83 | KMT2A (0.66) | KEAP1CA1CA2KMT2AHTR6 | |
| SCHEMBL5673665 | 0.78 | POLB (0.69) | KEAP1CA1CA2HTR6POLB | |
| SCHEMBL29653769 | 0.78 | CA1 (0.64) | KEAP1CA1CA2KMT2AHTR6 | |
| SCHEMBL798074 | 0.78 | CA1 (0.64) | KEAP1CA1CA2KMT2AHTR6 | |
| SCHEMBL1302465 | 0.75 | CA1 (0.61) | KEAP1CA1CA2KMT2AHTR6 | |
| SCHEMBL31120812 | 0.75 | CA1 (0.61) | KEAP1CA1CA2KMT2AHTR6 | |
| SCHEMBL29011157 | 0.75 | CA1 (0.61) | KEAP1CA1CA2KMT2AHTR6 | |
| SCHEMBL6822933 | 0.75 | CA1 (0.61) | KEAP1CA1CA2KMT2AHTR6 | |
| Potassium SCHEMBL29568431 | 0.75 | CA1 (0.61) | KEAP1CA1CA2KMT2AHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0004287-B1 | DISULFIMIDE DERIVATIVES CONTAINING POLYMERISABLE MALEIMIDE GROUPS, PROCESS FOR THEIR PREPARATION AND THEIR USE | BAYER AG (DE) | 1981-03-25 | — | — | EP | disclosed |
| EP-0004287-A2 | Disulfimide derivatives containing polymerisable maleimide groups, process for their preparation and their use | BAYER AG (DE) | 1979-10-03 | — | — | EP | disclosed |