Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | LPAR3 | Q9UBY5 | 6/20 | 0.44 |
| ▸ | LPAR2 | Q9HBW0 | 4/20 | 0.44 |
| ▸ | TRPM8 | Q7Z2W7 | 8/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11309165 | 1.00 | TSHR (0.44) | TSHRTHRBLPAR3LPAR2TRPM8 | |
| SCHEMBL9784617 | 1.00 | TSHR (0.44) | TSHRTHRBLPAR3LPAR2TRPM8 | |
| SCHEMBL10790012 | 1.00 | TSHR (0.44) | TSHRTHRBLPAR3LPAR2TRPM8 | |
| SCHEMBL28389335 | 1.00 | TSHR (0.44) | TSHRTHRBLPAR3LPAR2TRPM8 | |
| SCHEMBL9808098 | 1.00 | TSHR (0.44) | TSHRTHRBLPAR3LPAR2TRPM8 | |
| SCHEMBL28217258 | 0.97 | LPAR3 (0.42) | TSHRTHRBLPAR3LPAR2TRPM8 | |
| SCHEMBL3132754 | 0.97 | LPAR3 (0.40) | TSHRTHRBLPAR3LPAR2TRPM8 | |
| SCHEMBL9808102 | 0.88 | TSHR (0.35) | TSHRTHRBLPAR3LPAR2TRPM8 | |
| SCHEMBL14860553 | 0.86 | LPAR3 (0.37) | TSHRTHRBLPAR3LPAR2TRPM8 | |
| SCHEMBL28264253 | 0.86 | TSHR (0.33) | TSHRTHRBLPAR3LPAR2TRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4308214-A | REACTION OF SULFUR WITH DIALKYLPHOSPHINE FOLLOWED BY NEUTRALIZATION | CYANAMID CANADA INC. (CA) | 1981-12-29 | — | — | US | disclosed |