Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11345257 | 0.62 | MEN1 (0.33) | — | |
| SCHEMBL24669870 | 0.60 | RECQL (0.35) | RECQLHTTSMN1; SMN2 | |
| SCHEMBL12689695 | 0.60 | CYP2A6 (0.36) | RECQL | |
| Hydrochloric Acid SCHEMBL2179951 | 0.59 | CYP2A6 (0.35) | RECQL | |
| SCHEMBL116289 | 0.56 | — | — | |
| SCHEMBL28892524 | 0.55 | — | — | |
| SCHEMBL23399524 | 0.55 | — | — | |
| SCHEMBL1637329 | 0.55 | HDAC8 (0.39) | HTTSMN1; SMN2 | |
| SCHEMBL10408804 | 0.53 | KDM4E (0.31) | HPGDTDP1 | |
| SCHEMBL25423635 | 0.53 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4275073-A | PENTATHIEPINOPYRAZOLES AND PYRAZOLOTRITHIOCARBONATES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-06-23 | — | — | US | disclosed |