SCHEMBL11345002

SCHEMBL11345002

CCCSP(=O)(OCC)Oc1ccc(S(=O)(=O)Oc2ccccc2)cc1

nearest known ligand 0.45

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CA12 O43570 4/20 0.45
CA1 P00915 4/20 0.45
CA2 P00918 4/20 0.45
CA4 P22748 4/20 0.45
CA5A P35218 4/20 0.45
CA7 P43166 4/20 0.45
CA9 Q16790 4/20 0.45
CA5B Q9Y2D0 4/20 0.45
TDP1 Q9NUW8 2/20 0.41
GAA P10253 1/20 0.41
MAPK1 P28482 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11665748 0.96 TDP1 (0.43) CA12CA1CA2CA4CA5A
SCHEMBL11341828 0.91 ENPP1 (0.43) CA12CA1CA2CA4CA5A
SCHEMBL11662772 0.91 ENPP1 (0.43) CA12CA1CA2CA4CA5A
SCHEMBL11330947 0.91 TDP1 (0.41) CA12CA1CA2CA4CA5A
SCHEMBL11341661 0.89 TDP1 (0.45) CA12CA1CA2CA4CA5A
SCHEMBL11334200 0.88 CA12 (0.36) CA12CA1CA2CA4CA5A
SCHEMBL11348292 0.88 CA12 (0.40) CA12CA1CA2CA4CA5A
SCHEMBL11662931 0.88 GAA (0.40) CA12CA1CA2CA4CA5A
SCHEMBL11756213 0.86 CA12 (0.47) CA12CA1CA2CA4CA5A
SCHEMBL11341616 0.86 CA1 (0.52) CA1CA2CA9GAAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4287189-A USEFUL AS PESTICIDES ROHM AND HAAS COMPANY (US) 1981-09-01 US disclosed