⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6050221 | 1.00 | — | — | |
| SCHEMBL8645511 | 0.87 | — | — | |
| SCHEMBL1834611 | 0.83 | TDP1 (0.36) | — | |
| SCHEMBL20509901 | 0.83 | TDP1 (0.36) | — | |
| SCHEMBL1840460 | 0.83 | TDP1 (0.36) | — | |
| SCHEMBL1845796 | 0.83 | TDP1 (0.36) | — | |
| SCHEMBL20526404 | 0.83 | TDP1 (0.36) | — | |
| SCHEMBL3291304 | 0.83 | TDP1 (0.36) | — | |
| SCHEMBL6690910 | 0.83 | TDP1 (0.36) | — | |
| SCHEMBL27583386 | 0.83 | TDP1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4272546-A | ANTILIPEMIC, ANTIATHEROSCLEROTIC | AMERICAN CYANAMID COMPANY (US) | 1981-06-09 | — | — | US | disclosed |
| US-4254138-A | ANTILIPEMIC AGENTS AND ANTIATHEROSCLEROTIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1981-03-03 | — | — | US | disclosed |