Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | HPGD | P15428 | 6/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 3/20 | 0.47 |
| ▸ | CA9 | Q16790 | 3/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11349683 | 0.92 | KDM4E (0.51) | KDM4EALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL29385965 | 0.92 | KDM4E (0.51) | KDM4EALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL29543502 | 0.92 | CA12 (0.48) | KDM4EALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL11350787 | 0.90 | KDM4E (0.46) | KDM4EALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL31301807 | 0.90 | KDM4E (0.46) | KDM4EALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL14941064 | 0.87 | CA12 (0.48) | KDM4EALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL30510955 | 0.87 | CA12 (0.48) | KDM4EALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL11354452 | 0.86 | CA12 (0.46) | KDM4EALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL7206896 | 0.86 | KDM4E (0.47) | KDM4EALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL7206886 | 0.86 | KDM4E (0.47) | KDM4EALDH1A1HPGDHSD17B10KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0000063-B1 | DIPEPTIDE DERIVATIVES OF 7-(N-ALPHA-SUBSTITUTED OR NON-SUBSTITUTED X-ARGINYL)-AMINO-4-METHYL-COUMARIN | AJINOMOTO CO., INC. (JP) | 1981-06-10 | — | — | EP | disclosed |
| EP-0000063-A1 | Dipeptide derivatives of 7-(N-alpha-substituted or non-substituted X-arginyl)-amino-4-methyl-coumarin | AJINOMOTO CO., INC. (JP) | 1978-12-20 | — | — | EP | disclosed |