SCHEMBL11345853

SCHEMBL11345853

O=C1N=C(O)CCN1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL535025 0.70
SCHEMBL31735157 0.66 CRBN (0.32)
SCHEMBL21846228 0.65
SCHEMBL18961875 0.65 CRBN (0.36)
SCHEMBL964388 0.63
SCHEMBL31735118 0.63 CRBN (0.33)
SCHEMBL42430 0.61
SCHEMBL11853640 0.60 CRBN (0.39)
Methyl Alcohol SCHEMBL28207339 0.60
Hydantoin SCHEMBL9391323 0.60

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0005162-B1 PROCESS FOR PREPARING 5,5-DISUBSTITUTED 4-CARBAMIDO-HEXAHYDROPYRIMIDINES BASF Aktiengesellschaft (DE) 1981-12-30 EP disclosed
EP-0005504-A1 Process for the preparation of 5,5-disubstituted-4-ureido-hexahydropyrimidines BASF Aktiengesellschaft (DE) 1979-11-28 EP disclosed
EP-0005162-A1 Process for preparing 5,5-disubstituted 4-carbamido-hexahydropyrimidines BASF Aktiengesellschaft (DE) 1979-11-14 EP disclosed
EP-0004608-A1 4-Acylamido-hexahydropyrimidines, and process for their preparation BASF Aktiengesellschaft (DE) 1979-10-17 EP disclosed