Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 5/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9170054 | 0.76 | MCL1 (0.58) | MCL1ALDH1A1CYP3A4KMT2AHSD17B10 | |
| SCHEMBL5154225 | 0.75 | — | — | |
| SCHEMBL21315459 | 0.75 | MCL1 (0.58) | MCL1ALDH1A1CYP3A4CYP1A2KMT2A | |
| SCHEMBL11386268 | 0.74 | MCL1 (0.56) | MCL1ALDH1A1CYP3A4CYP1A2KMT2A | |
| SCHEMBL20068039 | 0.74 | MCL1 (0.56) | MCL1ALDH1A1CYP3A4CYP1A2KMT2A | |
| SCHEMBL215502 | 0.73 | — | — | |
| SCHEMBL11336511 | 0.73 | GAA (0.35) | ALDH1A1CYP1A2GAAKDM4ECYP2C19 | |
| SCHEMBL13291442 | 0.73 | — | — | |
| SCHEMBL1417434 | 0.73 | — | — | |
| SCHEMBL6217575 | 0.72 | MCL1 (0.74) | MCL1ALDH1A1CYP3A4CYP1A2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8575337-B2 | Oxazolidinone derivative having fused ring | RESEARCH FOUNDATION ITSUU LABORATORY (JP) | 2013-11-05 | — | — | US | disclosed |
| US-4287298-A | AND A POLYESTER COATED WITH A COPOLYMER MADE FROM VINYLIDINE CHLORIDE, AN ALKYL ACRYLATE AND AN ALLYL OR VINYL MONOMER | CIBA-GEIGY AG (CH) | 1981-09-01 | — | — | US | disclosed |
| US-4244988-A | Method of coating linear polyester with aqueous latex | CIBA-GEIGY AG (CH) | 1981-01-13 | — | — | US | disclosed |
| US-4167593-A | Method of subbing a polyester base | CIBA-GEIGY AG (CH) | 1979-09-11 | — | — | US | disclosed |
| US-4098953-A | BIAXIALLY ORIENTED SYNTHETIC LINEAR POLYESTER FILM BASE MATERIAL WITH COPOLYMER SUBBING LAYER | CIBA-GEIGY AG (CH) | 1978-07-04 | — | — | US | disclosed |