Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.59 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10586017 | 0.81 | GRIN2B (0.50) | GRIN2BOPRM1OPRL1NPC1RAB9A | |
| SCHEMBL1240954 | 0.81 | TAAR1 (0.84) | TAAR1GRIN2BOPRM1OPRL1SMN1; SMN2 | |
| SCHEMBL21792273 | 0.81 | TAAR1 (0.84) | TAAR1GRIN2BOPRM1OPRL1SMN1; SMN2 | |
| SCHEMBL5332051 | 0.81 | TAAR1 (0.84) | TAAR1GRIN2BOPRM1OPRL1SMN1; SMN2 | |
| SCHEMBL25002632 | 0.81 | TAAR1 (0.84) | TAAR1GRIN2BOPRM1OPRL1SMN1; SMN2 | |
| SCHEMBL24075499 | 0.81 | TAAR1 (0.84) | TAAR1GRIN2BOPRM1OPRL1SMN1; SMN2 | |
| SCHEMBL3665298 | 0.81 | TAAR1 (0.84) | TAAR1GRIN2BOPRM1OPRL1SMN1; SMN2 | |
| SCHEMBL24767088 | 0.81 | TAAR1 (0.84) | TAAR1GRIN2BOPRM1OPRL1SMN1; SMN2 | |
| SCHEMBL22216853 | 0.81 | TAAR1 (0.84) | TAAR1GRIN2BOPRM1OPRL1SMN1; SMN2 | |
| SCHEMBL3907332 | 0.79 | TAAR1 (0.81) | TAAR1GRIN2BOPRM1OPRL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE30837-E | ANTIDEPRESSANTS | THE UPJOHN COMPANY (US) | 1981-12-29 | — | — | US | disclosed |
| US-4169156-A | ANTIDEPRESSANTS | THE UPJOHN COMPANY (US) | 1979-09-25 | — | — | US | disclosed |