Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 6/20 | 0.65 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.65 |
| ▸ | CHRND | Q07001 | 5/20 | 0.61 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.61 |
| ▸ | CHRNG | P07510 | 1/20 | 0.61 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.61 |
| ▸ | GRIA1 | P42261 | 3/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11348361 | 1.00 | HDAC1 (0.65) | HDAC1HDAC6CHRNDCHRNA1CHRNG | |
| SCHEMBL9203106 | 0.90 | MDM4 (0.64) | HDAC1HDAC6CHRND | |
| SCHEMBL9203104 | 0.90 | MDM4 (0.64) | HDAC1HDAC6CHRND | |
| SCHEMBL14472130 | 0.89 | HDAC1 (0.66) | HDAC1HDAC6GRIA1 | |
| SCHEMBL27910970 | 0.89 | HDAC1 (0.66) | HDAC1HDAC6GRIA1 | |
| SCHEMBL18220518 | 0.89 | HDAC1 (0.66) | HDAC1HDAC6GRIA1 | |
| SCHEMBL14472192 | 0.89 | HDAC1 (0.66) | HDAC1HDAC6GRIA1 | |
| SCHEMBL2337076 | 0.89 | HDAC1 (0.66) | HDAC1HDAC6GRIA1 | |
| SCHEMBL43741 | 0.87 | HDAC1 (0.64) | HDAC1HDAC6GRIA1 | |
| SCHEMBL42986 | 0.87 | HDAC1 (0.64) | HDAC1HDAC6GRIA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4277460-A | RADIOACTIVE IODINE | DAIICHI RADIOISOTOPE LABORATORIES, LTD. (JP) | 1981-07-07 | — | — | US | disclosed |
| US-4190593-A | AMIDES OF 6-ALPHA-CARBOXYMETHYLTHIOCORTISOL | DAIICHI RADIOISOTOPE LABORATORIES, LTD. (JP) | 1980-02-26 | — | — | US | disclosed |