SCHEMBL11354571

SCHEMBL11354571

O=[N+]([O-])c1cc(C(c2ccc(-c3ccccc3)cc2)n2cncn2)ccc1Cl

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 16/20 0.50
CYP26A1 O43174 2/20 0.49
CYP11B1 P15538 2/20 0.40
STS P08842 1/20 0.40
CYP3A4 P08684 2/20 0.40
CYP2C19 P33261 2/20 0.40
MAPT P10636 2/20 0.40
MEN1 O00255 1/20 0.40
CYP1A2 P05177 1/20 0.40
CYP2D6 P10635 1/20 0.40
CYP2C9 P11712 1/20 0.40
HTT P42858 1/20 0.40
RECQL P46063 1/20 0.40
KMT2A Q03164 1/20 0.40
TSHR P16473 1/20 0.40
CYP11B2 P19099 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9524092 0.94 CYP19A1 (0.57) CYP19A1CYP26A1CYP11B1STSCYP3A4
SCHEMBL11361986 0.80 CYP17A1 (0.62) CYP19A1CYP26A1CYP11B1CYP3A4MAPT
SCHEMBL11367077 0.79 CYP19A1 (0.79) CYP19A1CYP26A1CYP11B1CYP3A4CYP2C19
SCHEMBL11355223 0.78 CYP19A1 (0.79) CYP19A1CYP26A1CYP11B1CYP3A4CYP2C19
SCHEMBL7413890 0.78 CYP19A1 (0.83) CYP19A1CYP26A1CYP11B1CYP3A4CYP2C19
SCHEMBL11353444 0.77 CYP19A1 (0.63) CYP19A1CYP26A1CYP11B1CYP3A4CYP2C19
SCHEMBL10102443 0.77 CYP19A1 (0.60) CYP19A1CYP11B1STSCYP3A4CYP2C19
SCHEMBL11365362 0.77 CYP19A1 (0.58) CYP19A1CYP26A1CYP11B1CYP3A4CYP2C19
SCHEMBL11354164 0.75 CYP19A1 (0.60) CYP19A1CYP26A1CYP11B1
SCHEMBL11355092 0.75 CYP19A1 (0.79) CYP19A1CYP26A1CYP11B1CYP3A4CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4243670-A MICROBORICIDES; FUNGICIDES; SPORICIDES; HYGIENE BAYER AKTIENGESELLSCHAFT (DE) 1981-01-06 US disclosed