Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 3/20 | 0.43 |
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11738168 | 0.99 | CNR2 (0.42) | CNR2CNR1 | |
| SCHEMBL11837937 | 0.92 | CNR2 (0.42) | CNR2CNR1 | |
| SCHEMBL14456000 | 0.91 | CNR2 (0.45) | CNR2 | |
| SCHEMBL11554822 | 0.86 | CNR2 (0.43) | CNR2 | |
| SCHEMBL11712333 | 0.86 | CNR2 (0.55) | CNR2CNR1 | |
| SCHEMBL11557352 | 0.86 | CNR2 (0.42) | CNR2 | |
| SCHEMBL11322652 | 0.85 | CNR2 (0.43) | CNR2CNR1 | |
| SCHEMBL11558702 | 0.85 | CNR2 (0.42) | CNR2 | |
| SCHEMBL11635728 | 0.84 | CNR2 (0.44) | CNR2CNR1 | |
| SCHEMBL11555538 | 0.84 | CNR2 (0.41) | CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4287192-A | Antiglaucoma agents | ABBOTT LABORATORIES (US) | 1981-09-01 | — | — | US | disclosed |
| US-4248874-A | QUINUCLIDINE DERIVATIVES | ABBOTT LABORATORIES (US) | 1981-02-03 | — | — | US | disclosed |
| US-4247557-A | Benzopyranopyridines as antiglaucoma agents | ABBOTT LABORATORIES (US) | 1981-01-27 | — | — | US | disclosed |
| US-4217351-A | Benzopyrano quinuclidines useful as antiglaucoma agents | ABBOTT LABORATORIES (US) | 1980-08-12 | — | — | US | disclosed |
| US-4136183-A | BENZOPYRANOPYRIDINES AS ANTIGLAUCOMA AGENTS | ABBOTT LABORATORIES (US) | 1979-01-23 | — | — | US | disclosed |
| US-4042694-A | ANALGESICS | SHARPS ASSOCIATES (US) | 1977-08-16 | — | — | US | disclosed |
| US-4025630-A | Anesthesia methods using benzopyrans and esters thereof as pre-anesthesia medication | ABBOTT LABORATORIES (US) | 1977-05-24 | — | — | US | disclosed |
| US-3991194-A | Heterocyclic esters of benzopyranopyridines | SHARPS ASSOCIATES (US) | 1976-11-09 | — | — | US | disclosed |
| US-3883657-A | 5,5-Dimethyl-10-hydroxy-8-(3-methyl-2-octyl)-2-(2-propynyl)-1,2,3,4-tetrahydro-5h-{8 1{9 -benzopyrano{8 3,4-d{9 pyridine as a sedative hypnotic | SHARPS ASS | 1975-05-13 | — | — | US | disclosed |
| US-3798326-A | 5,5-DIMETHYL-10-HYDROXY-8-(3-METHYL-2-OCTYL)-2-(2-PROPYNYL)-1,2,3,4-TETRAHYDRO-5H-(1)BENZOPYRANO(3,4-D)PYRIDINE AS AN ANTI-HYPERTENSIVE AGENT | SHARPS ASS | 1974-03-19 | — | — | US | disclosed |
| US-3795736-A | 5,5-DIMETHYL-10-HYDROXY-8-(3-METHYL-2-OCTYL)-2-(2-PROPYNYL)-1,2,3,4-TETRAHYDRO-5H-(1) BENZOPYRANO(3,4-D)PYRIDINE AS AN ANALGESIC AGENT | SHARPS ASS | 1974-03-05 | — | — | US | disclosed |
| US-3777028-A | 5,5-DIMETHYL-10-HYDROXY-8-(3-METHYL-2-OCTYL)-2-(2-PROPYNYL)-1,2,3,4-TETRAHYDRO-5H-(1)-BENZOPYRANO(3,4-D)PYRIDINE AS AN ANTI-DIARRHEAL AGENT | SHARPS ASS | 1973-12-04 | — | — | US | disclosed |