Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11353409 | 0.86 | HSD17B10 (0.48) | MAPTKDM4EHTTTDP1SMN1; SMN2 | |
| SCHEMBL11351992 | 0.81 | HSD17B10 (0.54) | MAPTKDM4EHTTTDP1SMN1; SMN2 | |
| SCHEMBL10897219 | 0.74 | HSD17B10 (0.79) | MAPTKDM4EHTTTDP1SMN1; SMN2 | |
| SCHEMBL11021035 | 0.74 | HSD17B10 (0.79) | MAPTKDM4EHTTTDP1SMN1; SMN2 | |
| SCHEMBL11021033 | 0.74 | HSD17B10 (0.79) | MAPTKDM4EHTTTDP1SMN1; SMN2 | |
| SCHEMBL11358993 | 0.74 | KDM4E (0.46) | MAPTKDM4EHTTTDP1SMN1; SMN2 | |
| SCHEMBL11358989 | 0.74 | KDM4E (0.46) | MAPTKDM4EHTTTDP1SMN1; SMN2 | |
| SCHEMBL11358996 | 0.74 | KDM4E (0.46) | MAPTKDM4EHTTTDP1SMN1; SMN2 | |
| SCHEMBL11359504 | 0.73 | KDM4E (0.65) | MAPTKDM4EHTTTDP1SMN1; SMN2 | |
| SCHEMBL11355400 | 0.71 | HSD17B10 (0.51) | MAPTKDM4EHTTTDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4264497-A | ANTICHOLINERGIC, ANTISPASMODIC, ANTIULCER AND ANTISECRETORY AGENTS | MARUKO SEIYAKU CO., LTD. (JP) | 1981-04-28 | — | — | US | disclosed |