Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 9/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.49 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.48 |
| ▸ | SLC22A6 | Q4U2R8 | 3/20 | 0.48 |
| ▸ | SLC22A8 | Q8TCC7 | 3/20 | 0.48 |
| ▸ | DNMT1 | P26358 | 2/20 | 0.48 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.48 |
| ▸ | SLC22A11 | Q9NSA0 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 2/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | SPOP | O43791 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11386047 | 0.96 | PTGS1 (0.59) | PTGS1L3MBTL1MAPTTDP1NR1I2 | |
| SCHEMBL11352380 | 0.91 | PTGS1 (0.55) | PTGS1L3MBTL1MAPTTDP1NR1I2 | |
| SCHEMBL11358244 | 0.90 | PTGS1 (0.54) | PTGS1L3MBTL1MAPTTDP1NR1I2 | |
| SCHEMBL11356751 | 0.90 | PTGS1 (0.51) | PTGS1L3MBTL1MAPTTDP1NR1I2 | |
| SCHEMBL11376741 | 0.89 | PTGS1 (0.58) | PTGS1L3MBTL1MAPTTDP1NR1I2 | |
| SCHEMBL11361566 | 0.88 | PTGS1 (0.53) | PTGS1L3MBTL1MAPTTDP1NR1I2 | |
| SCHEMBL11360177 | 0.88 | PTGS1 (0.53) | PTGS1L3MBTL1MAPTTDP1NR1I2 | |
| SCHEMBL11383045 | 0.87 | PTGS1 (0.61) | PTGS1L3MBTL1MAPTTDP1NR1I2 | |
| SCHEMBL11378592 | 0.86 | PTGS1 (0.60) | PTGS1L3MBTL1MAPTTDP1NR1I2 | |
| SCHEMBL11387837 | 0.85 | PTGS1 (0.57) | PTGS1L3MBTL1MAPTTDP1NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4285940-A | ANTIBIOTICS | EISAI CO., LTD. (JP) | 1981-08-25 | — | — | US | disclosed |