Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11347332 | 0.84 | BCHE (0.38) | AKR1C3AKR1C2KDM4EHSD17B10CYP1A2 | |
| SCHEMBL11410230 | 0.84 | NQO1 (0.45) | NQO1LTA4HAKR1C3AKR1C2MEN1 | |
| SCHEMBL11357091 | 0.83 | NQO1 (0.43) | NQO1LTA4HAKR1C3AKR1C2KDM4E | |
| SCHEMBL11353112 | 0.81 | NQO1 (0.45) | NQO1LTA4HAKR1C3AKR1C2KDM4E | |
| SCHEMBL11353201 | 0.79 | NQO1 (0.43) | NQO1LTA4HAKR1C3AKR1C2KDM4E | |
| SCHEMBL6322208 | 0.78 | NQO1 (0.50) | NQO1LTA4HKDM4EMEN1KMT2A | |
| SCHEMBL11349853 | 0.72 | NQO1 (0.58) | NQO1LTA4HAKR1C3AKR1C2KDM4E | |
| SCHEMBL12062656 | 0.72 | NQO1 (0.52) | NQO1LTA4HKDM4EMEN1KMT2A | |
| SCHEMBL19309934 | 0.71 | NQO1 (0.50) | NQO1LTA4HKDM4EMEN1KMT2A | |
| SCHEMBL2218714 | 0.71 | NQO1 (0.50) | NQO1LTA4HKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0001910-B1 | PREPARATION OF 4,4'-DIHYDROXY STILBENES OR DERIVATIVES THEREOF | MONSANTO COMPANY (US) | 1981-09-02 | — | — | EP | disclosed |
| US-4189610-A | Preparation of 4,4-dioxy-substituted stilbenes | MONSANTO COMPANY (US) | 1980-02-19 | — | — | US | disclosed |
| EP-0001910-A1 | Preparation of 4,4'-dihydroxy stilbenes or derivatives thereof | MONSANTO COMPANY (US) | 1979-05-16 | — | — | EP | disclosed |