Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.39 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.39 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ASPH | Q12797 | 1/20 | 0.37 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.37 |
| ▸ | DTYMK | P23919 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11352637 | 1.00 | MAPT (0.49) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL11303911 | 0.80 | MAPT (0.52) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL11365205 | 0.79 | POLB (0.38) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL11297858 | 0.77 | MEN1 (0.49) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL11308852 | 0.75 | PDE7A (0.45) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL11297851 | 0.72 | MAPT (0.49) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL11297209 | 0.72 | MAPT (0.49) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL11292807 | 0.72 | MAPT (0.49) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL2028311 | 0.70 | SLC6A2 (0.68) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL3715267 | 0.70 | MAPT (0.53) | MAPTKDM4EALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4342859-A | Bis(aminophenylthioalkyl)terephthalate and hardener for polyurethane elastomer thereof | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 1982-08-03 | — | — | US | disclosed |