Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 10/20 | 0.45 |
| ▸ | ESR1 | P03372 | 6/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | XBP1 | P17861 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | TYMS | P04818 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9437447 | 0.83 | ESR2 (0.56) | ESR2ESR1MAPTMEN1ALDH1A1 | |
| SCHEMBL11366251 | 0.76 | ESR1 (0.54) | ESR2ESR1MAPTGAAXBP1 | |
| SCHEMBL13379648 | 0.76 | ESR2 (0.54) | ESR2ESR1MAPTMEN1ALDH1A1 | |
| SCHEMBL544625 | 0.71 | ESR2 (0.72) | ESR2ESR1MMP2MMP9MAPT | |
| SCHEMBL16349984 | 0.71 | ESR2 (0.52) | ESR2ESR1MAPTGAAXBP1 | |
| SCHEMBL4457760 | 0.70 | ESR2 (0.42) | ESR2ESR1MAPTGAAXBP1 | |
| SCHEMBL9066583 | 0.70 | ESR2 (0.50) | ESR2ESR1KMT2A | |
| SCHEMBL11358090 | 0.69 | KMT2A (0.63) | ESR2ESR1MMP2MMP9MAPT | |
| SCHEMBL13379659 | 0.69 | ESR2 (0.45) | ESR2ESR1MAPTGAAXBP1 | |
| SCHEMBL2045619 | 0.68 | ESR2 (0.62) | ESR2ESR1MMP2MMP9MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4247484-A | Keto-diphenol compounds | GENERAL ELECTRIC COMPANY (US) | 1981-01-27 | — | — | US | disclosed |