Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.31 |
| ▸ | CNR1 | P21554 | 2/20 | 0.31 |
| ▸ | CNR2 | P34972 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19860621 | 0.82 | — | — | |
| SCHEMBL11037969 | 0.81 | — | — | |
| SCHEMBL11039916 | 0.81 | — | — | |
| SCHEMBL11041050 | 0.80 | MEN1 (0.30) | MAPT | |
| SCHEMBL25160924 | 0.80 | TLR4 (0.33) | TLR4TSHR | |
| SCHEMBL11039914 | 0.79 | — | — | |
| SCHEMBL20052288 | 0.78 | — | — | |
| SCHEMBL11036276 | 0.78 | — | — | |
| SCHEMBL11043028 | 0.78 | — | — | |
| SCHEMBL11042432 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2125935-B1 | IMPROVED SYNTHESIS OF CATIONIC SILOXANE PREPOLYMERS | BAUSCH & LOMB (US) | 2011-02-23 | — | — | EP | disclosed |
| WO-2009070438-A1 | OPTICAL MATERIAL AND METHOD FOR MODIFYING THE REFRACTIVE INDEX | BAUSCH & LOMB INCORPORATED (US) | 2009-06-04 | — | — | WO | disclosed |
| WO-2008039654-A2 | WATER SOLUBLE SILICONE MACROMONOMERS FOR OPHTHALMIC MATERIALS | BAUSCH & LOMB INCORPORATED (US) | 2008-04-03 | — | — | WO | disclosed |