Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.31 |
| ▸ | QPCT | Q16769 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11509745 | 0.83 | BCHE (0.35) | BCHEACHE | |
| SCHEMBL11511503 | 0.81 | HRH4 (0.35) | BCHEACHEQPCT | |
| SCHEMBL11509994 | 0.80 | HRH4 (0.33) | BCHEACHEQPCT | |
| SCHEMBL11527455 | 0.79 | BCHE (0.35) | BCHEACHEP2RX7QPCT | |
| SCHEMBL11509742 | 0.77 | BCHE (0.35) | BCHEACHE | |
| SCHEMBL11509738 | 0.77 | BCHE (0.35) | BCHEACHE | |
| SCHEMBL11511501 | 0.74 | HRH4 (0.35) | BCHEACHEQPCT | |
| SCHEMBL11372646 | 0.74 | QPCT (0.47) | BCHEACHEQPCT | |
| SCHEMBL9821764 | 0.74 | QPCT (0.47) | BCHEACHEQPCT | |
| SCHEMBL11527427 | 0.73 | HRH4 (0.40) | BCHEACHEQPCT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4158013-A | N-Cyano-N'-alkynyl-N\"-2-mercaptoethylguanidines | BRISTOL-MYERS COMPANY (US) | 1979-06-12 | — | — | US | claimed |
| US-4289876-A | HISTAMINE H2 RECEPTOR BLOCKING AGENTS, ANTIULCER | BRISTOL-MYERS COMPANY (US) | 1981-09-15 | — | — | US | disclosed |
| US-4282363-A | ANTIULCER | BRISTOL-MYERS COMPANY (US) | 1981-08-04 | — | — | US | disclosed |
| US-4250316-A | Pyridyl guanidine anti-ulcer agents | BRISTOL-MYERS COMPANY (US) | 1981-02-10 | — | — | US | disclosed |
| US-4203909-A | ANTIULCER | BRISTOL-MYERS COMPANY (US) | 1980-05-20 | — | — | US | disclosed |
| US-4200578-A | ANTIULCER AGENTS, BLOCKING AGENTS, ANTISECRETORY AGENTS | BRISTOL-MYERS COMPANY (US) | 1980-04-29 | — | — | US | disclosed |
| US-4158013-A | N-Cyano-N'-alkynyl-N\"-2-mercaptoethylguanidines | BRISTOL-MYERS COMPANY (US) | 1979-06-12 | — | — | US | disclosed |
| US-4157340-A | N,N'-[Bis(N-cyanoguanyl)]cystamine derivatives | BRISTOL-MEYERS COMPANY (US) | 1979-06-05 | — | — | US | disclosed |