⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16843594 | 0.79 | — | — | |
| SCHEMBL10588655 | 0.79 | — | — | |
| SCHEMBL20005028 | 0.76 | ANPEP (0.32) | — | |
| SCHEMBL7895114 | 0.75 | — | — | |
| SCHEMBL3857603 | 0.75 | — | — | |
| SCHEMBL67913 | 0.75 | — | — | |
| SCHEMBL27961444 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL17159560 | 0.72 | — | — | |
| SCHEMBL16151 | 0.71 | — | — | |
| SCHEMBL16111087 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2027104-B1 | ARYLSULFONYLCHROMANS AS 5-HT6 INHIBITORS | HOFFMANN LA ROCHE (CH) | 2011-02-23 | — | — | EP | disclosed |
| EP-1658069-A1 | HETEROCYCLIC AMIDE DERIVATIVES WHICH POSSESS GLYCOGEN PHOSPHORYLASE INHIBITORY ACTIVITY | Astrazeneca AB (SE) | 2006-05-24 | — | — | EP | disclosed |
| WO-2005013981-A1 | HETEROCYCLIC AMIDE DERIVATIVES WHICH POSSESS GLYCOGEN PHOSPHORYLASE INHIBITORY ACTIVITY | ASTRAZENECA AB (SE) | 2005-02-17 | — | — | WO | disclosed |
| EP-0064833-A2 | High pressure liquid affinity chromatography | The Public Health Laboratory Service Board (GB) | 1982-11-17 | — | — | EP | disclosed |