Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.55 |
| ▸ | NR1I2 | O75469 | 6/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.55 |
| ▸ | PGR | P06401 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | ALB | P02768 | 1/20 | 0.52 |
| ▸ | PPARG | P37231 | 1/20 | 0.52 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.52 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.52 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.52 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HTR2C | P28335 | 1/20 | 0.51 |
| ▸ | APEX1 | P27695 | 2/20 | 0.49 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11256876 | 0.94 | NR1I2 (0.60) | TDP1NR1I2HSD17B10PGRALDH1A1 | |
| SCHEMBL11365397 | 0.90 | MAPT (0.52) | TDP1NR1I2HSD17B10PGRALDH1A1 | |
| SCHEMBL11365299 | 0.89 | TDP1 (0.68) | TDP1NR1I2HSD17B10PGRALDH1A1 | |
| SCHEMBL10838359 | 0.89 | TDP1 (0.68) | TDP1NR1I2HSD17B10PGRALDH1A1 | |
| SCHEMBL10838364 | 0.89 | TDP1 (0.68) | TDP1NR1I2HSD17B10PGRALDH1A1 | |
| SCHEMBL11371127 | 0.87 | MAPT (0.50) | TDP1NR1I2HSD17B10PGRALDH1A1 | |
| SCHEMBL11371926 | 0.84 | MAPT (0.54) | TDP1NR1I2HSD17B10PGRALDH1A1 | |
| SCHEMBL9021538 | 0.83 | MAPT (0.74) | TDP1NR1I2HSD17B10PGRALDH1A1 | |
| SCHEMBL8486403 | 0.83 | MAPT (0.74) | TDP1NR1I2HSD17B10PGRALDH1A1 | |
| SCHEMBL8486400 | 0.83 | MAPT (0.74) | TDP1NR1I2HSD17B10PGRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0022245-A2 | Aminothiadiazolyl derivatives, process for their preparation, pharmaceutical compositions containing them;starting compounds and process for their preparation | CIBA-GEIGY AG (CH) | 1981-01-14 | — | — | EP | disclosed |