Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 6/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | FBP1 | P09467 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | PLG | P00747 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11370912 | 0.83 | ATM (0.41) | ATMPPARGPPARAKDM4EPRSS1 | |
| SCHEMBL2008777 | 0.83 | MAOB (0.47) | CNR2PPARGPPARAMAOBKDM4E | |
| SCHEMBL3928629 | 0.83 | CNR2 (0.50) | CNR2PPARGPPARAMAOBMAPT | |
| SCHEMBL5216184 | 0.81 | NPSR1 (0.49) | ATMCNR2POLBMAPTTHRB | |
| SCHEMBL9692544 | 0.80 | KMT2A (0.51) | CNR2PPARGPPARAMAOBMAPT | |
| SCHEMBL2060134 | 0.78 | CNR2 (0.52) | CNR2PPARGPPARAMAOBF2 | |
| SCHEMBL29281054 | 0.78 | POLB (0.49) | ATMPOLBMAPTTHRBNPSR1 | |
| SCHEMBL10732623 | 0.78 | PRSS1 (0.52) | ATMPPARGPPARAFAAHMAPT | |
| SCHEMBL1077335 | 0.77 | CNR2 (0.42) | ATMCNR2PPARGPPARAMAOB | |
| SCHEMBL3923273 | 0.77 | CNR2 (0.51) | CNR2PPARGPPARAMAOBPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0003552-B1 | POLYMERS WITH LATERAL TRICYCLIC IMIDYL GROUPS, CROSS-LINKABLE BY THE ACTION OF LIGHT, THEIR PREPARATION AND THEIR USE | CIBA-GEIGY AG (CH) | 1982-05-26 | — | — | EP | disclosed |
| US-4285958-A | ANTIALLERGENS; ANTIHISTAMINES; BRONCHODILATOR AGENTS | RICHARDSON-MERRELL INC. (US) | 1981-08-25 | — | — | US | disclosed |
| US-4285957-A | ANTIALLERGENS; ANTIHISTAMINES; BRONCHODILATOR AGENTS | RICHARDSON-MERRELL INC. (US) | 1981-08-25 | — | — | US | disclosed |
| US-4254130-A | ANTIALLERGENS | RICHARDSON-MERRELL INC. (US) | 1981-03-03 | — | — | US | disclosed |
| US-4254129-A | ANTIALLERGENS, BRONCHODILATORS, ANTIHISTAMINES; 4-DIPHENYLMETHYL PIPERIDINO-ALKANOLS | RICHARDSON-MERRELL INC. (US) | 1981-03-03 | — | — | US | disclosed |