Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 6/20 | 0.34 |
| ▸ | KCNK3 | O14649 | 6/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11258194 | 0.99 | KCNA5 (0.34) | KCNA5KCNK3SMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL11265109 | 0.96 | KDM4E (0.36) | KCNA5KCNK3SMN1; SMN2KDM4EHSD17B10 | |
| Hydrochloric Acid SCHEMBL11259201 | 0.95 | KDM4E (0.35) | KCNA5KCNK3SMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL11270721 | 0.91 | KCNA5 (0.35) | KCNA5KCNK3SMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL11265096 | 0.88 | KCNK3 (0.39) | KCNA5KCNK3SMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL11269520 | 0.87 | KDM4E (0.36) | KCNA5KCNK3SMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL11302963 | 0.86 | KDM4E (0.33) | SMN1; SMN2KDM4EHSD17B10HPGDTSHR | |
| SCHEMBL11261736 | 0.86 | KCNK3 (0.38) | KCNA5KCNK3SMN1; SMN2KDM4EHSD17B10 | |
| Hydrochloric Acid SCHEMBL11269660 | 0.86 | KDM4E (0.33) | SMN1; SMN2KDM4EHSD17B10HPGDTSHR | |
| SCHEMBL11274218 | 0.86 | GAA (0.36) | SMN1; SMN2KDM4EHSD17B10HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4248885-A | FOR GASTROINTESTINAL, UROGENITAL, RHEUMATIC, AND CARDIOVASCULAR DISEASE | SOCIETE D'ETUDES SCIENTIFIQUES ET INDUSTRIELLES DE L'ILE-DE-FRANCE (FR) | 1981-02-03 | — | — | US | claimed |
| US-4186135-A | TREATMENT OF PSYCHOLOGICAL DISORDERS | SOCIETE D'ETUDES SCIENTIFIQUES ET INDUSTRIELLES DE L'ILE-DE-FRANCE (FR) | 1980-01-29 | — | — | US | claimed |