Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.43 |
| ▸ | HTR3A | P46098 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.43 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.42 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.42 |
| ▸ | ACP1 | P24666 | 2/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1581852 | 0.83 | GBA1 (0.62) | GBA1KCNH2SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL894700 | 0.83 | GBA1 (0.66) | GBA1KCNH2SLC6A4HTR3APRMT5 | |
| Hydrochloric Acid SCHEMBL7403430 | 0.82 | GBA1 (0.61) | GBA1KCNH2SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL13576622 | 0.82 | EED (0.54) | KCNH2SLC6A4SLC6A2SLC6A3P2RX7 | |
| Hydrochloric Acid SCHEMBL6968488 | 0.81 | GBA1 (0.63) | GBA1KCNH2SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL3166228 | 0.80 | GBA1 (0.62) | GBA1SLC6A4HTR2CHTR2BACP1 | |
| Hydrochloric Acid SCHEMBL18280022 | 0.79 | SLC6A4 (0.55) | GBA1KCNH2SLC6A4SLC6A2SLC6A3 | |
| Hydrochloric Acid SCHEMBL18280203 | 0.79 | GBA1 (0.61) | GBA1SLC6A4SLC6A2SLC6A3HTR2C | |
| SCHEMBL28128625 | 0.78 | SLC6A4 (0.63) | GBA1KCNH2SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL1691782 | 0.78 | PRMT5 (0.65) | GBA1KCNH2SLC6A4SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4246268-A | ANTIPSYCHOTICS, TRANQUILIZERS, NEUROLEPTICS COMPOUNDS AND NOVEL INTERMEDIATES | RICHARDSON-MERRELL INC. (US) | 1981-01-20 | — | — | US | disclosed |