Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 4/20 | 0.56 |
| ▸ | PI4KA | P42356 | 3/20 | 0.56 |
| ▸ | PI4K2B | Q8TCG2 | 3/20 | 0.56 |
| ▸ | PI4K2A | Q9BTU6 | 3/20 | 0.56 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.53 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.53 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | THPO | P40225 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CTSL | P07711 | 2/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2954550 | 0.79 | ADORA2A (0.66) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL17352601 | 0.78 | ADORA2A (0.65) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL10763696 | 0.77 | ADORA2A (0.62) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL11807186 | 0.76 | ADORA2A (0.63) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL11454981 | 0.76 | ADORA2A (0.58) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL11363312 | 0.76 | ADORA2A (0.58) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL21057419 | 0.75 | PDE8B (0.38) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL8166306 | 0.75 | ADORA2A (0.61) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL11370037 | 0.74 | ADORA2A (0.56) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL11360552 | 0.74 | CYP1A2 (0.60) | ADORA2API4KAPI4K2BPI4K2API4KB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4286093-A | 9-Cyclohexyl-2-alkoxy-9H-adenine process | MEAD JOHNSON & COMPANY (US) | 1981-08-25 | — | — | US | disclosed |