⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL679132 | 0.81 | TSHR (0.31) | — | |
| SCHEMBL15752983 | 0.78 | — | — | |
| SCHEMBL4433760 | 0.75 | — | — | |
| SCHEMBL702302 | 0.75 | — | — | |
| SCHEMBL28151673 | 0.73 | — | — | |
| SCHEMBL9625861 | 0.73 | — | — | |
| SCHEMBL9625649 | 0.73 | — | — | |
| SCHEMBL2971115 | 0.73 | TSHR (0.50) | — | |
| SCHEMBL25199890 | 0.71 | — | — | |
| SCHEMBL2952150 | 0.71 | TSHR (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4245056-A | Crosslinking high density polyethylene with t-octyl silicon peroxides | ARGUS CHEMICAL CORPORATION (US) | 1981-01-13 | — | — | US | disclosed |
| US-4245056-A | Crosslinking high density polyethylene with t-octyl silicon peroxides | ARGUS CHEMICAL CORPORATION (US) | 1981-01-13 | — | — | US | disclosed |
| US-4198337-A | CURING CATALYSTS | ARGUS CHEMICAL CORPORATION (US) | 1980-04-15 | — | — | US | disclosed |
| US-4198337-A | CURING CATALYSTS | ARGUS CHEMICAL CORPORATION (US) | 1980-04-15 | — | — | US | disclosed |
| EP-0009070-A1 | t-Octyl silicon peroxides and their use for crosslinking polyethylenes | Argus Chemical Corporation (US) | 1980-04-02 | — | — | EP | disclosed |