Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPM1B | O75688 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12415445 | 0.90 | PPM1B (0.35) | PPM1BPTPN1PPP1CCKDM4EGLA | |
| SCHEMBL11372934 | 0.90 | TSHR (0.49) | TSHRHPGDHCAR2ALDH1A1 | |
| SCHEMBL882933 | 0.87 | CA1 (0.38) | PPM1BPTPN1PPP1CCALDH1A1NPSR1 | |
| SCHEMBL1128162 | 0.87 | CA1 (0.38) | PPM1BPTPN1PPP1CCALDH1A1NPSR1 | |
| SCHEMBL30158792 | 0.87 | CA1 (0.38) | PPM1BPTPN1PPP1CCALDH1A1NPSR1 | |
| SCHEMBL2127524 | 0.84 | PPM1B (0.39) | PPM1BPTPN1PPP1CCKDM4EGLA | |
| SCHEMBL12357210 | 0.84 | PPM1B (0.39) | PPM1BPTPN1PPP1CCKDM4EGLA | |
| SCHEMBL12415461 | 0.82 | PPM1B (0.45) | PPM1BPTPN1PPP1CCKDM4EGLA | |
| SCHEMBL1297333 | 0.80 | PPM1B (0.47) | PPM1BPTPN1PPP1CCKDM4EGLA | |
| SCHEMBL8274706 | 0.79 | TSHR (0.40) | TSHRGRM2GRM3ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0038271-A2 | Cyclopropane carboxylic acid derivatives, their preparation and use in combating parasites of plants and animals, their compositions and intermediates | ROUSSEL-UCLAF (FR) | 1981-10-21 | — | — | EP | disclosed |