Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | F7 | P08709 | 1/20 | 0.32 |
| ▸ | F3 | P13726 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11378700 | 0.88 | NPC1 (0.38) | NPC1RAB9AKDM4EMAPTLMNA | |
| SCHEMBL11384104 | 0.86 | NPC1 (0.38) | NPC1RAB9AKDM4EMAPTLMNA | |
| SCHEMBL11370081 | 0.82 | NPC1 (0.55) | NPC1RAB9AKDM4EMAPTLMNA | |
| SCHEMBL11418479 | 0.81 | NPC1 (0.51) | NPC1RAB9AKDM4EMAPTLMNA | |
| SCHEMBL1034829 | 0.81 | NPC1 (0.51) | NPC1RAB9AKDM4EMAPTLMNA | |
| SCHEMBL11371804 | 0.80 | NPC1 (0.44) | NPC1RAB9AKDM4EMAPTLMNA | |
| SCHEMBL11372316 | 0.80 | NPC1 (0.36) | NPC1RAB9AKDM4ELMNAMEN1 | |
| SCHEMBL11372446 | 0.79 | NPC1 (0.38) | NPC1RAB9ALMNAMEN1KMT2A | |
| SCHEMBL11379229 | 0.79 | NPC1 (0.38) | NPC1RAB9AMAPTLMNAMEN1 | |
| SCHEMBL3782539 | 0.78 | POLB (0.50) | NPC1RAB9AKDM4EMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4271307-A | Bichromophoric benzotriazole-benzoxazole ultraviolet stabilizers and their use in organic compositions | EASTMAN KODAK COMPANY (US) | 1981-06-02 | — | — | US | disclosed |
| US-4076687-A | Bichromophoric benzotriazole-benzoxazole ultraviolet stabilizers and their use in organic compositions | EASTMAN KODAK COMPANY (US) | 1978-02-28 | — | — | US | disclosed |