Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14955405 | 0.83 | TP53 (0.37) | TP53 | |
| SCHEMBL6720279 | 0.78 | SLC7A5 (0.40) | TP53 | |
| SCHEMBL11872650 | 0.76 | TSHR (0.33) | TP53 | |
| Hydrochloric Acid SCHEMBL27819023 | 0.76 | SLC7A5 (0.39) | TP53 | |
| SCHEMBL6687959 | 0.76 | TP53 (0.33) | TP53 | |
| SCHEMBL10028834 | 0.74 | TP53 (0.32) | TP53 | |
| SCHEMBL1766368 | 0.74 | TP53 (0.32) | TP53 | |
| SCHEMBL19034720 | 0.74 | TP53 (0.32) | TP53 | |
| SCHEMBL3381816 | 0.72 | — | — | |
| SCHEMBL11878195 | 0.72 | TP53 (0.35) | TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4287342-A | 2,4,6-Trihalo-5-alkyl-and 5-alkenylsulphonylpyrimidines | CIBA-GEIGY CORPORATION (US) | 1981-09-01 | — | — | US | disclosed |
| US-4188483-A | 5-Alkylsulphonyl- and 5-alkenylsulphonylbarbituric acids and derivatives thereof | CIBA-GEIGY CORPORATION (US) | 1980-02-12 | — | — | US | disclosed |