Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 4/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA7 | P43166 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11080188 | 0.84 | HTT (0.40) | HTTCA1CA2CA7CA9 | |
| SCHEMBL11080186 | 0.84 | HTT (0.40) | HTTCA1CA2CA7CA9 | |
| SCHEMBL11079291 | 0.83 | HTT (0.41) | HTTCA1CA2CA7CA9 | |
| SCHEMBL11079293 | 0.83 | HTT (0.41) | HTTCA1CA2CA7CA9 | |
| SCHEMBL11069316 | 0.82 | PTPN1 (0.49) | HTTCA1CA2CA7CA9 | |
| SCHEMBL11069313 | 0.82 | PTPN1 (0.49) | HTTCA1CA2CA7CA9 | |
| SCHEMBL11071383 | 0.81 | HTT (0.40) | HTTCA1CA2CA7CA9 | |
| SCHEMBL11071406 | 0.81 | HTT (0.40) | HTTCA1CA2CA7CA9 | |
| SCHEMBL11081443 | 0.79 | FOLH1 (0.45) | HTTCA1CA2CA7CA9 | |
| SCHEMBL11074774 | 0.78 | KDM1A (0.44) | HTTFOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0021775-A1 | Synthesis of 1RS,4SR,5RS-4-(4,8-dimethyl-5-hydroxy-7-nonen-1-yl)-4-methyl-3,8-dioxabicyclo(3.2.1)octane-1-acetic acid and intermediates | ORTHO PHARMACEUTICAL CORPORATION (US) | 1981-01-07 | — | — | EP | disclosed |