Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 2/20 | 0.60 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | THRB | P10828 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | APAF1 | O14727 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7714573 | 0.81 | ABL1 (0.55) | ABL1ALOX5PTGS1PTGS2NOTUM | |
| SCHEMBL11374154 | 0.75 | ABL1 (0.57) | ABL1ALOX5PTGS1PTGS2NOTUM | |
| SCHEMBL1357063 | 0.75 | ABL1 (1.00) | ABL1ALOX5PTGS1PTGS2MAPT | |
| SCHEMBL11371307 | 0.74 | ABL1 (0.70) | ABL1ALOX5PTGS1PTGS2NOTUM | |
| Hydrochloric Acid SCHEMBL11089748 | 0.74 | ABL1 (0.97) | ABL1ALOX5PTGS1PTGS2MAPT | |
| SCHEMBL11384175 | 0.70 | ABL1 (0.44) | ABL1ALOX5PTGS1PTGS2 | |
| SCHEMBL7719911 | 0.69 | ABL1 (0.77) | ABL1ALOX5PTGS1PTGS2ALDH1A1 | |
| SCHEMBL11189086 | 0.69 | ABL1 (0.42) | ABL1ALOX5PTGS1PTGS2MAPT | |
| SCHEMBL908024 | 0.68 | ABL1 (0.67) | ABL1ALOX5PTGS1PTGS2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL10956641 | 0.68 | ABL1 (0.53) | ABL1ALOX5PTGS1PTGS2NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4268436-A | OXIDATIVE DIAZOTIZATION WITH NITROSYLSULFURIC ACID, ALKALINE METAL NITRITES, OR ALKYL NITRITES | AZIENDE COLORI NAZIONALI AFFINI ACNA S.P.A. (IT) | 1981-05-19 | — | — | US | disclosed |