Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 15/20 | 0.68 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.45 |
| ▸ | PRKCH | P24723 | 1/20 | 0.44 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11366557 | 0.86 | SYK (0.69) | SYKNR4A2ADORA2AADORA1PRKCH | |
| SCHEMBL11364757 | 0.85 | SYK (0.60) | SYKNR4A2ALDH1A1 | |
| SCHEMBL22271112 | 0.85 | SYK (0.68) | SYKADORA2AADORA1PRKCHPRKCE | |
| SCHEMBL11379518 | 0.84 | SYK (0.68) | SYKNR4A2PRKCHPRKCE | |
| SCHEMBL11365024 | 0.81 | SYK (1.00) | SYKKDM4EALDH1A1GLAGAA | |
| SCHEMBL11372183 | 0.81 | SYK (0.64) | SYKADORA2APRKCHPRKCE | |
| SCHEMBL11371341 | 0.81 | SYK (0.67) | SYKKDM4EALDH1A1RAB9A | |
| SCHEMBL11372368 | 0.79 | SYK (0.60) | SYKNR4A2PRKCHPRKCEKDM4E | |
| SCHEMBL11377728 | 0.79 | SYK (0.60) | SYKADORA2APRKCHPRKCEKDM4E | |
| SCHEMBL11371826 | 0.78 | SYK (0.52) | SYKNR4A2ADORA2AADORA1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4260759-A | CONDENSATION OF NITRILES | SCHERING-CORPORATION (US) | 1981-04-07 | — | — | US | disclosed |
| US-4115395-A | FUNGICIDES, BACTERICIDES | SCHERING CORPORATION (US) | 1978-09-19 | — | — | US | disclosed |
| US-4107166-A | ANTIFUNGAL, ANTIBACTERIAL | SCHERING CORPORATION (US) | 1978-08-15 | — | — | US | disclosed |
| US-4017500-A | FUNGICIDES, BACTERICIDES | SCHERING CORPORATION (US) | 1977-04-12 | — | — | US | disclosed |