SCHEMBL1137016

SCHEMBL1137016

Cc1ccc([Mg]c2ccc(C)cc2C)c(C)c1

nearest known ligand 0.46

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 5/20 0.46
TP53 P04637 2/20 0.46
CYP2A6 P11509 4/20 0.41
CYP1A2 P05177 4/20 0.41
ALDH1A1 P00352 1/20 0.40
RAPGEF4 Q8WZA2 3/20 0.38
ACHE P22303 3/20 0.37
CYP3A4 P08684 2/20 0.36
THRB P10828 1/20 0.36
ALOX15 P16050 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
TRPA1 O75762 1/20 0.36
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
ADRA2A P08913 1/20 0.34
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1314124 0.79 TDP1 (0.42) TDP1TP53CYP2A6CYP1A2ALDH1A1
SCHEMBL1021714 0.79 TDP1 (0.42) TDP1TP53CYP2A6CYP1A2ALDH1A1
SCHEMBL1316329 0.79 TDP1 (0.42) TDP1TP53CYP2A6CYP1A2ALDH1A1
SCHEMBL10318858 0.78 TDP1 (0.46) TDP1TP53CYP2A6CYP1A2ALDH1A1
SCHEMBL19744496 0.69 TDP1 (0.55) TDP1TP53CYP2A6CYP1A2ALDH1A1
SCHEMBL60541 0.69
SCHEMBL1135726 0.69 TDP1 (0.55) TDP1TP53CYP2A6CYP1A2ALDH1A1
SCHEMBL29365203 0.69
SCHEMBL8117972 0.67 TDP1 (0.52) TDP1TP53CYP2A6CYP1A2ALDH1A1
SCHEMBL3043421 0.67 TDP1 (0.52) TDP1TP53CYP2A6CYP1A2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 184 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3519466-B1 METHOD FOR LONG CHAIN BRANCHING CONTROL IN POLYETHYLENE PRODUCTION UNIVATION TECH LLC (US) 2023-07-05 EP disclosed
US-11459413-B2 Process control for long chain branching control in polyethylene production UNIVATION TECHNOLOGIES, LLC (US) 2022-10-04 US disclosed
US-20210284768-A1 PROCESS CONTROL FOR LONG CHAIN BRANCHING CONTROL IN POLYETHYLENE PRODUCTION UNIVATION TECHNOLOGIES, LLC (US) 2021-09-16 US disclosed
EP-3041888-B1 POLYETHYLENES WITH INCREASED MOLECULAR WEIGHT DISTRIBUTION UNIVATION TECH LLC (US) 2021-02-17 EP disclosed
EP-2841471-B1 ACTIVATOR COMPOSITIONS, THEIR PREPARATION, AND THEIR USE IN CATALYSTS GRACE W R & CO (US) 2020-05-06 EP disclosed
US-10513572-B2 Process control for long chain branching control in polyethylene production UNIVATION TECHNOLOGIES, LLC (US) 2019-12-24 US disclosed
EP-2800766-B1 METHODS FOR MAKING CATALYST COMPOSITIONS AND POLYMER PRODUCTS PRODUCED THEREFROM UNIVATION TECH LLC (US) 2019-09-04 EP disclosed
EP-3519466-A1 METHOD FOR LONG CHAIN BRANCHING CONTROL IN POLYETHYLENE PRODUCTION Univation Technologies, LLC (US) 2019-08-07 EP disclosed
US-20190153135-A1 Activator Compositions, Their Preparation, And Their Use In Catalysts GRACE W R & CO (US) 2019-05-23 US disclosed
US-10221264-B2 Activator compositions, their preparation, and their use in catalysts W. R. GRACE & CO.-CONN. (US) 2019-03-05 US disclosed
US-4565797-A COORDINATION CATALYSTS HAVING HIGH ACTIVITY AND GOOD HYDROGEN RESPONSE FOR MOLECULAR WEIGHT CONTROL FOR POLYMERIZING ALPHA-OLEFINS; HIGH STRENGTH FILMS EXXON RESEARCH & ENGINEERING CO. (US) 1986-01-21 US disclosed
US-4565796-A COORDINATION CATALYSTS HAVING HIGH ACTIVITY AND GOOD HYDROGEN RESPONSE FOR MOLECULAR WEIGHT CONTROL FOR POLYMERIZING ALPHA-OLEFINS; HIGH STRENGTH FILMS EXXON RESEARCH & ENGINEERING CO. (US) 1986-01-21 US disclosed
US-4564606-A HALOGEN; METAL HYDROCARBYL COMPOUND; ACYLHALIDE, TRANSISTION METAL EXXON RESEARCH & ENGINEERING CO. (US) 1986-01-14 US disclosed
US-4558025-A COORDINATION CATALYST EXXON RESEARCH & ENGINEERING CO. (US) 1985-12-10 US disclosed
US-4558024-A COORDINATION CATALYST EXXON RESEARCH & ENGINEERING CO. (US) 1985-12-10 US disclosed
EP-0114434-A1 Catalyst and polymerization of olefins with that catalyst STAMICARBON B.V. (NL) 1984-08-01 EP disclosed
US-4174431-A CATALYST COMPRISING DIHYDROCARBYL MAGNESIUM AND ORGANIC ALKALI METAL COMPOUND THE FIRESTONE TIRE & RUBBER COMPANY (US) 1979-11-13 US disclosed
US-4173547-A Catalyst for preparing polyalkenes STAMICARBON, B.V. (NL) 1979-11-06 US disclosed
US-4139490-A HIGH MOLECULAR WEIGHT POLYBUTADIENE THE FIRESTONE TIRE & RUBBER COMPANY (US) 1979-02-13 US disclosed
US-4097659-A Process of polymerizing α-olefins in the liquid phase STAMICARBON, N.V. (NL) 1978-06-27 US disclosed