Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | CA12 | O43570 | 6/20 | 0.60 |
| ▸ | CA1 | P00915 | 6/20 | 0.60 |
| ▸ | CA2 | P00918 | 6/20 | 0.60 |
| ▸ | CA7 | P43166 | 6/20 | 0.60 |
| ▸ | CA9 | Q16790 | 6/20 | 0.60 |
| ▸ | CA14 | Q9ULX7 | 6/20 | 0.60 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.58 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15892265 | 0.93 | CYP1A2 (0.56) | CYP1A2CA12CA1CA2CA7 | |
| SCHEMBL12161238 | 0.93 | CYP1A2 (0.56) | CYP1A2CA12CA1CA2CA7 | |
| SCHEMBL12161172 | 0.91 | CYP1A2 (0.54) | CYP1A2CA12CA1CA2CA7 | |
| SCHEMBL8922334 | 0.88 | CYP1A2 (0.51) | CYP1A2CA12CA1CA2CA7 | |
| SCHEMBL16477773 | 0.88 | CA12 (0.51) | CYP1A2CA12CA1CA2CA7 | |
| SCHEMBL12853621 | 0.86 | CYP1A2 (0.49) | CYP1A2CA12CA1CA2CA7 | |
| SCHEMBL862340 | 0.86 | CYP1A2 (0.66) | CYP1A2CA12CA1CA2CA7 | |
| SCHEMBL16472392 | 0.84 | CYP1A2 (0.63) | CYP1A2CA12CA1CA2CA7 | |
| SCHEMBL9128544 | 0.84 | CYP1A2 (0.63) | CYP1A2CA12CA1CA2CA7 | |
| SCHEMBL17594960 | 0.83 | CYP1A2 (0.57) | CYP1A2CA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 150 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118317957-A | Macrocyclic-containing compounds and radiolabeled complexes thereof as ligands in targeted radiotherapy applications | 墨尔本大学 | 2024-07-09 | — | — | CN | disclosed |
| US-RE49918-E1 | Cytotoxic benzodiazepine derivatives | IMMUNOGEN, INC. (US) | 2024-04-16 | — | — | US | disclosed |
| CN-114099676-B | Synthetic method of self-assembly vesicle-like structure based on porphyrin molecule system | 河南师范大学 | 2023-03-31 | — | — | CN | disclosed |
| CN-114099676-A | Synthetic method of self-assembly vesicle-like structure based on porphyrin molecule system | 河南师范大学 | 2022-03-01 | — | — | CN | disclosed |
| CN-107335061-B | Cytotoxic benzodiazepine derivatives | 伊缪诺金公司 | 2021-09-07 | — | — | CN | disclosed |
| CN-107531693-B | 5 or 8-substituted imidazo [1, 5-a ] pyridines as indoleamine, tryptophan dioxygenase inhibitors | 百济神州有限公司 | 2021-07-06 | — | — | CN | disclosed |
| US-20210171883-A1 | ANTIVIRAL WIPER | FUJIFILM CORPORATION (JP) | 2021-06-10 | — | — | US | disclosed |
| EP-3280715-B1 | NOVEL 5 OR 8-SUBSTITUTED IMIDAZO [1, 5-a]PYRIDINES AS INDOLEAMINE AND/OR TRYPTOPHANE 2, 3-DIOXYGENASES | BEIGENE LTD (KY) | 2020-11-25 | — | — | EP | disclosed |
| EP-3280715-B1 | NOVEL 5 OR 8-SUBSTITUTED IMIDAZO [1, 5-a]PYRIDINES AS INDOLEAMINE AND/OR TRYPTOPHANE 2, 3-DIOXYGENASES | BEIGENE LTD (KY) | 2020-11-25 | — | — | EP | disclosed |
| EP-3666289-A1 | CYTOTOXIC BENZODIAZEPINE DERIVATIVES | ImmunoGen, Inc. (US) | 2020-06-17 | — | — | EP | disclosed |
| US-6893716-B2 | Non-covalent assembly of multilayer thin film supramolecular structures | WORCESTER POLYTECHNIC INSTITUTE (US) | 2005-05-17 | — | — | US | disclosed |
| US-20040110009-A1 | Non-covalent assembly of multilayer thin film supramolecular structures | WORCESTER POLYTECHNIC INSTITUTE | 2004-06-10 | — | — | US | disclosed |
| EP-1379525-A2 | HETEROPOLYCYCLIC COMPOUNDS AND THEIR USE AS METABOTROPIC GLUTAMATE RECEPTOR ANTAGONISTS | NPS PHARMACEUTICALS, INC. (US) | 2004-01-14 | — | — | EP | disclosed |
| US-6660753-B2 | For therapy of stroke, head trauma, anoxic injury, ischemic injury, hypoglycemia, epilepsy, pain, migraine headaches, Parkinson's disease, senile dementia, Huntington's Chorea, anxiety, and Alzheimer's disease | NPS PHARMACEUTICALS, INC. | 2003-12-09 | — | — | US | disclosed |
| US-20030055085-A1 | Heteropolycyclic compounds and their use as metabotropic glutamate receptor antagonists | ASTRAZENECA AB (SE) | 2003-03-20 | — | — | US | disclosed |
| WO-2002068417-A3 | HETEROPOLYCYCLIC COMPOUNDS AND THEIR USE AS METABOTROPIC GLUTAMATE RECEPTOR ANTAGONISTS | SLASSI ABDELMALIK (CA) | 2002-11-14 | — | — | WO | disclosed |
| WO-2002068417-A2 | HETEROPOLYCYCLIC COMPOUNDS AND THEIR USE AS METABOTROPIC GLUTAMATE RECEPTOR ANTAGONISTS | NPS PHARMACEUTICALS, INC. (US) | 2002-09-06 | — | — | WO | disclosed |
| US-6127390-A | ANTITUMOR AGENTS INHIBITING FARNESYL-PROTEIN TRANSFERASE, FOR TREATING CANCER | MERCK & CO., INC. (US) | 2000-10-03 | — | — | US | disclosed |
| EP-1019391-A1 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO. INC. (US) | 2000-07-19 | — | — | EP | disclosed |
| WO-1999018096-A1 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1999-04-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210171883-A1 | ANTIVIRAL WIPER | CGAS, PRKX, PDE4C | CYP1A2 3532/4885CA12 2396/4885CA1 2414/4885 |
| US-20030055085-A1 | Heteropolycyclic compounds and their use as metabotropic glutamate receptor antagonists | GRM2, GRIN2A, GRM1 | CYP1A2 4298/4885CA12 3922/4885CA1 972/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.