Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.46 |
| ▸ | PDE4A | P27815 | 4/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.39 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11040495 | 0.89 | CNR1 (0.46) | CNR1CNR2PDE4BPDE4APDE4C | |
| SCHEMBL10979002 | 0.88 | CNR1 (0.51) | CNR1CNR2PDE4BPDE4APDE4C | |
| Hydrochloric Acid SCHEMBL10974497 | 0.86 | CNR1 (0.47) | CNR1CNR2PDE4BPDE4APDE4C | |
| SCHEMBL10973972 | 0.86 | CNR1 (0.57) | CNR1CNR2PDE4BPDE4APDE4C | |
| SCHEMBL11284777 | 0.85 | CNR1 (0.48) | CNR1CNR2PDE4BPDE4APDE4C | |
| SCHEMBL11075597 | 0.85 | CNR1 (0.56) | CNR1CNR2PDE4BPDE4APDE4C | |
| SCHEMBL10975710 | 0.85 | CNR1 (0.54) | CNR1CNR2PDE4BPDE4APDE4C | |
| SCHEMBL10976332 | 0.83 | CNR1 (0.60) | CNR1CNR2PDE4BPDE4APDE4C | |
| SCHEMBL1826000 | 0.83 | CNR1 (0.52) | CNR1CNR2PDE4BPDE4APDE4C | |
| SCHEMBL1827713 | 0.83 | CNR1 (0.52) | CNR1CNR2PDE4BPDE4APDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4276295-A | VASODILATORS, HYPOTENSIVE, ANTIATHEROSCLEROTIC | Ishikawa, Masayuki (JP) | 1981-06-30 | — | — | US | disclosed |