Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 7/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12504116 | 1.00 | TSHR (0.44) | TSHRTHRBALDH1A1DNM1LMNA | |
| SCHEMBL11310792 | 1.00 | TSHR (0.44) | TSHRTHRBALDH1A1DNM1LMNA | |
| SCHEMBL5687408 | 1.00 | TSHR (0.44) | TSHRTHRBALDH1A1DNM1LMNA | |
| SCHEMBL5685340 | 1.00 | TSHR (0.44) | TSHRTHRBALDH1A1DNM1LMNA | |
| SCHEMBL5026589 | 1.00 | TSHR (0.44) | TSHRTHRBALDH1A1DNM1LMNA | |
| SCHEMBL11771482 | 0.97 | TSHR (0.39) | TSHRTHRBALDH1A1DNM1LMNA | |
| SCHEMBL135669 | 0.88 | TSHR (0.50) | TSHRTHRBALDH1A1DNM1LMNA | |
| SCHEMBL132353 | 0.88 | TSHR (0.50) | TSHRTHRBALDH1A1DNM1LMNA | |
| SCHEMBL21817819 | 0.88 | TSHR (0.50) | TSHRTHRBALDH1A1DNM1LMNA | |
| SCHEMBL134147 | 0.88 | TSHR (0.50) | TSHRTHRBALDH1A1DNM1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2658877-B1 | STABILIZATION OF POLYMERS THAT CONTAIN A HYDROLYZABLE FUNCTIONALITY | BRIDGESTONE CORP (JP) | 2023-04-12 | — | — | EP | disclosed |
| US-9546237-B2 | Stabilization of polymers that contain a hydrolyzable functionality | BRIDGESTONE CORPORATION (JP) | 2017-01-17 | — | — | US | disclosed |
| US-9499683-B2 | Stabilization of polymers that contain a hydrolyzable functionality | BRIDGESTONE CORPORATION (JP) | 2016-11-22 | — | — | US | disclosed |
| CN-102040224-B | Hydrophobic core-shell silica particle, hollow silica particle, and manufacturing methods thereof | ADEKA CORP | 2015-07-15 | — | — | CN | disclosed |
| US-20140031471-A1 | Stabilization Of Polymers That Contain A Hydrolyzable Functionality | BRIDGESTONE CORPORATION (JP) | 2014-01-30 | — | — | US | disclosed |
| US-20130331520-A1 | STABILIZATION OF POLYMERS THAT CONTAIN A HYDROLYZABLE FUNCTIONALITY | BRIDGESTONE CORPORATION (JP) | 2013-12-12 | — | — | US | disclosed |
| EP-2658877-A1 | STABILIZATION OF POLYMERS THAT CONTAIN A HYDROLYZABLE FUNCTIONALITY | Bridgestone Corporation (JP) | 2013-11-06 | — | — | EP | disclosed |
| WO-2012092626-A1 | STABILIZATION OF POLYMERS THAT CONTAIN A HYDROLYZABLE FUNCTIONALITY | BRIDGESTONE CORPORATION (JP) | 2012-07-05 | — | — | WO | disclosed |
| CN-102040224-A | Hydrophobic core-shell silica particle, hollow silica particle, and manufacturing methods thereof | ADEKA CORP | 2011-05-04 | — | — | CN | disclosed |
| US-4257957-A | Methyl-tris-(4-hydroxycoumarin)silane | GENERAL ELECTRIC COMPANY (US) | 1981-03-24 | — | — | US | disclosed |
| US-4210596-A | Silyl ethers of 1,3-dicarbonyl cyclic compounds | GENERAL ELECTRIC COMPANY (US) | 1980-07-01 | — | — | US | disclosed |