SCHEMBL11373307

SCHEMBL11373307

N#CSc1cc(N)c(N)cc1Br

nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.47
USP8 P40818 1/20 0.47
USP5 P45974 1/20 0.47
USP4 Q13107 1/20 0.47
USP7 Q93009 1/20 0.47
POLB P06746 2/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
ALDH1A1 P00352 2/20 0.34
MAPT P10636 2/20 0.34
MYC P01106 4/20 0.32
WDR5 P61964 4/20 0.32
HTT P42858 2/20 0.31
CA2 P00918 1/20 0.31
CA5A P35218 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10414207 0.89 USP2 (0.45) USP2USP8USP5USP4USP7
SCHEMBL11173991 0.79 USP2 (0.56) USP2USP8USP5USP4USP7
SCHEMBL11367939 0.78 USP2 (0.47) USP2USP8USP5USP4USP7
SCHEMBL11374071 0.74 USP2 (0.47) USP2USP8USP5USP4USP7
SCHEMBL11374139 0.74 USP2 (0.47) USP2USP8USP5USP4USP7
SCHEMBL11367517 0.74 POLB (0.41) POLBL3MBTL1ALDH1A1MAPT
SCHEMBL28428884 0.72 USP2 (0.41) USP2USP8USP5USP4USP7
SCHEMBL10412909 0.72 USP2 (0.60) USP2USP8USP5USP4USP7
SCHEMBL9541164 0.71 KDM4E (0.43) POLBL3MBTL1ALDH1A1MAPTHTT
SCHEMBL26944306 0.70 USP2 (0.38) USP2USP8USP5USP4USP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4259344-A FUNGICIDES, ANTHELMINTICS CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA R.T. (HU) 1981-03-31 US disclosed