Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 11/20 | 0.67 |
| ▸ | CNR2 | P34972 | 11/20 | 0.67 |
| ▸ | ABHD12 | Q8N2K0 | 3/20 | 0.61 |
| ▸ | ABHD6 | Q9BV23 | 3/20 | 0.61 |
| ▸ | FAAH | O00519 | 2/20 | 0.61 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.61 |
| ▸ | LDHA | P00338 | 1/20 | 0.61 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.61 |
| ▸ | GPR183 | P32249 | 1/20 | 0.61 |
| ▸ | DRD3 | P35462 | 1/20 | 0.61 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.61 |
| ▸ | GPR18 | Q14330 | 1/20 | 0.61 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.61 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.61 |
| ▸ | KDR | P35968 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13280342 | 0.97 | CNR2 (0.71) | CNR1CNR2ABHD12ABHD6FAAH | |
| SCHEMBL16781742 | 0.97 | CNR2 (0.71) | CNR1CNR2ABHD12ABHD6FAAH | |
| SCHEMBL31545090 | 0.97 | CNR2 (0.71) | CNR1CNR2ABHD12ABHD6FAAH | |
| SCHEMBL22787424 | 0.97 | CNR2 (0.71) | CNR1CNR2ABHD12ABHD6FAAH | |
| SCHEMBL13280340 | 0.97 | CNR2 (0.71) | CNR1CNR2ABHD12ABHD6FAAH | |
| SCHEMBL29407185 | 0.97 | CNR2 (0.71) | CNR1CNR2ABHD12ABHD6FAAH | |
| SCHEMBL31545582 | 0.90 | CNR2 (0.66) | CNR1CNR2ABHD12ABHD6FAAH | |
| SCHEMBL11373352 | 0.87 | CNR1 (0.72) | CNR1CNR2ABHD12ABHD6FAAH | |
| SCHEMBL31545884 | 0.87 | CNR1 (0.72) | CNR1CNR2ABHD12ABHD6FAAH | |
| SCHEMBL15558108 | 0.85 | CNR2 (0.72) | CNR1CNR2ABHD12ABHD6FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4243674-A | HYPOTENSIVE AGENTS; ANALGESICS; ANTISECRETORY AGENTS; ANTIBODY INHIBITORS, AND TRANQUILIZERS | PFIZER INC. (US) | 1981-01-06 | — | — | US | disclosed |
| US-4143139-A | ANALGESICS, HYPOTENSIVES, IMMUNOSUPPRESSANTS, TRANQUILIZERS, ANTISECRETORY, ANTI-ANXIETY | PFIZER INC. (US) | 1979-03-06 | — | — | US | disclosed |