Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11375827 | 1.00 | MAPK1 (0.50) | MAPK1 | |
| SCHEMBL12858723 | 0.83 | MAPK1 (0.60) | MAPK1 | |
| SCHEMBL18974066 | 0.80 | MAPK1 (0.46) | MAPK1 | |
| SCHEMBL12285564 | 0.76 | MAPK1 (0.52) | MAPK1 | |
| SCHEMBL14901100 | 0.76 | MAPK1 (0.52) | MAPK1 | |
| SCHEMBL14901099 | 0.76 | MAPK1 (0.52) | MAPK1 | |
| SCHEMBL4181754 | 0.74 | MAPK1 (0.56) | MAPK1 | |
| SCHEMBL4189322 | 0.74 | MAPK1 (0.56) | MAPK1 | |
| SCHEMBL14901114 | 0.74 | MAPK1 (0.50) | MAPK1 | |
| SCHEMBL5427806 | 0.74 | MAPK1 (0.50) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4277610-A | Synthesis of 2,6,10-trimethyl-undecan-1-ol | HOFFMANN-LA ROCHE INC. (US) | 1981-07-07 | — | — | US | disclosed |
| US-4180682-A | Unsaturated alcohols having an ether protected group | HOFFMANN-LA ROCHE INC. (US) | 1979-12-25 | — | — | US | disclosed |
| US-4172958-A | Ethers of 2,6,10-trimethyl-undecan-1-ols | HOFFMANN-LA ROCHE INC. (US) | 1979-10-30 | — | — | US | disclosed |
| US-4169209-A | Ethers of 2,6-dimethyl-octane-1,8-diols | HOFFMANN-LA ROCHE INC. (US) | 1979-09-25 | — | — | US | disclosed |
| US-4163021-A | Synthesis of 2,6,10-trimethyl-undecan-1-ol | HOFFMANN-LA ROCHE INC. (US) | 1979-07-31 | — | — | US | disclosed |
| US-4140723-A | Intermediate compounds for producing vitamin E | HOFFMANN-LA ROCHE INC. (US) | 1979-02-20 | — | — | US | disclosed |
| US-4140702-A | Process for producing vitamin E intermediate compounds | HOFFMANN-LA ROCHE INC. (US) | 1979-02-20 | — | — | US | disclosed |
| US-4111961-A | Silicon ester of carboxylic acid | HOFFMANN-LA ROCHE INC. (US) | 1978-09-05 | — | — | US | disclosed |
| US-4107183-A | Synthesis of optically active carboxylic acid esters | HOFFMANN-LA ROCHE INC. (US) | 1978-08-15 | — | — | US | disclosed |
| US-4041058-A | Synthesis of 2,6,10-trimethyl-undecan-1-ol | HOFFMANN-LA ROCHE INC. (US) | 1977-08-09 | — | — | US | disclosed |