Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.52 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | TPMT | P51580 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11377339 | 0.91 | MAPT (0.50) | MAPK1MAPTPOLBL3MBTL1OPRK1 | |
| SCHEMBL30511375 | 0.90 | MAPK1 (0.53) | MAPK1MAPTPOLBL3MBTL1OPRK1 | |
| SCHEMBL25198617 | 0.90 | MAPK1 (0.53) | MAPK1MAPTPOLBL3MBTL1OPRK1 | |
| SCHEMBL31440674 | 0.86 | MAPT (0.57) | MAPK1MAPTPOLBL3MBTL1OPRK1 | |
| SCHEMBL18038271 | 0.86 | MAPK1 (0.57) | MAPK1MAPTPOLBL3MBTL1OPRK1 | |
| SCHEMBL72992 | 0.86 | MAPT (0.57) | MAPK1MAPTPOLBL3MBTL1OPRK1 | |
| SCHEMBL5248286 | 0.84 | MAPK1 (0.56) | MAPK1MAPTPOLBL3MBTL1OPRK1 | |
| SCHEMBL72187 | 0.84 | MAPT (0.56) | MAPK1MAPTPOLBL3MBTL1OPRK1 | |
| SCHEMBL13285512 | 0.84 | MAPK1 (0.56) | MAPK1MAPTPOLBL3MBTL1OPRK1 | |
| SCHEMBL18227400 | 0.84 | MAPK1 (0.56) | MAPK1MAPTPOLBL3MBTL1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4260620-A | HYPOTENSIVE AGENTS | CIBA-GEIGY CORPORATION (US) | 1981-04-07 | — | — | US | disclosed |
| US-4202901-A | HYPOTENSIVE AGENTS | CIBA-GEIGY CORPORATION (US) | 1980-05-13 | — | — | US | disclosed |
| US-4197302-A | HYPOTENSIVE AGENTS, 5-ETHERIFIED, ALSO ESTERS, AMIDES, HYDRAZIDES | CIBA-GEIGY CORPORATION (US) | 1980-04-08 | — | — | US | disclosed |