Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11302394 | 0.89 | KDM4E (0.45) | KDM4EALDH1A1HSD17B10HPGDLMNA | |
| SCHEMBL2052137 | 0.85 | KDM4E (0.56) | KDM4EALDH1A1HSD17B10HPGDLMNA | |
| SCHEMBL7712284 | 0.84 | KDM4E (0.55) | KDM4EALDH1A1HSD17B10HPGDLMNA | |
| SCHEMBL4284963 | 0.83 | KMT2A (0.58) | KDM4EALDH1A1HSD17B10LMNACYP1A2 | |
| SCHEMBL31112624 | 0.83 | KMT2A (0.58) | KDM4EALDH1A1HSD17B10LMNACYP1A2 | |
| SCHEMBL22171706 | 0.82 | KDM4E (0.42) | KDM4EALDH1A1LMNACYP1A2CYP3A4 | |
| SCHEMBL3264286 | 0.82 | HTT (0.53) | KDM4EALDH1A1HSD17B10HPGDTP53 | |
| SCHEMBL12227226 | 0.81 | KMT2A (0.52) | KDM4EALDH1A1LMNACYP1A2CYP3A4 | |
| SCHEMBL5157619 | 0.81 | KDM4E (0.57) | KDM4EALDH1A1HSD17B10HPGDLMNA | |
| SCHEMBL861238 | 0.81 | KDM4E (0.51) | KDM4EALDH1A1LMNACYP1A2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4308180-A | TIRE TREADS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1981-12-29 | — | — | US | disclosed |