Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.41 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.41 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.41 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.41 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.41 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CSF1R | P07333 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MAT2A | P31153 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1795489 | 0.92 | HPGD (0.55) | HPGDKDM4EHRH3FGFR1SRC | |
| SCHEMBL1798361 | 0.89 | HPGD (0.59) | HPGDKDM4EHRH3FGFR1SRC | |
| SCHEMBL11385020 | 0.89 | POLB (0.50) | MAPTHRH3PSEN1PSEN2APH1B | |
| SCHEMBL11389969 | 0.87 | HPGD (0.51) | HPGDKDM4EMAPTFGFR1SRC | |
| SCHEMBL1794923 | 0.86 | HPGD (0.50) | HPGDKDM4EHRH3FGFR1SRC | |
| SCHEMBL11385638 | 0.85 | HPGD (0.54) | HPGDKDM4EMAPTFGFR1SRC | |
| SCHEMBL1795805 | 0.85 | HPGD (0.48) | HPGDKDM4EHRH3FGFR1SRC | |
| SCHEMBL26229304 | 0.84 | MAPT (0.48) | HPGDKDM4EMAPTALDH1A1CYP1A2 | |
| SCHEMBL11377826 | 0.83 | ATM (0.51) | HPGDKDM4EFGFR1SRCALDH1A1 | |
| SCHEMBL1798018 | 0.82 | HPGD (0.52) | HPGDKDM4EHRH3FGFR1SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4244954-A | Acridine compounds and methods of combatting viruses with them | STERLING DRUG INC. (US) | 1981-01-13 | — | — | US | disclosed |
| US-4150134-A | Aminoalkoxy substituted 9(aryl or aralkyl)-acridines | STERLING DRUG INC. (US) | 1979-04-17 | — | — | US | disclosed |