Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.79 |
| ▸ | MEN1 | O00255 | 3/20 | 0.79 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.79 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | CYP51A1 | Q16850 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.34 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.33 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.33 |
| ▸ | CYP3A7 | P24462 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12336847 | 0.91 | KMT2A (0.66) | KMT2AMEN1TDP1HSP90AA1POLB | |
| SCHEMBL11489337 | 0.88 | MEN1 (1.00) | KMT2AMEN1TDP1HSP90AA1POLB | |
| SCHEMBL29934164 | 0.88 | MEN1 (1.00) | KMT2AMEN1TDP1HSP90AA1POLB | |
| SCHEMBL21654 | 0.88 | MEN1 (1.00) | KMT2AMEN1TDP1HSP90AA1POLB | |
| SCHEMBL19304856 | 0.83 | KMT2A (0.74) | KMT2AMEN1TDP1HSP90AA1POLB | |
| SCHEMBL1966587 | 0.81 | MEN1 (0.56) | KMT2AMEN1TDP1HSP90AA1POLB | |
| Dichlorophen SCHEMBL8309241 | 0.81 | MEN1 (0.84) | KMT2AMEN1TDP1HSP90AA1POLB | |
| SCHEMBL11369815 | 0.81 | KMT2A (0.77) | KMT2AMEN1TDP1HSP90AA1POLB | |
| SCHEMBL10740834 | 0.80 | MEN1 (0.80) | KMT2AMEN1TDP1HSP90AA1POLB | |
| SCHEMBL10739338 | 0.80 | MEN1 (0.80) | KMT2AMEN1TDP1HSP90AA1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4243405-A | HYDROXYALKYLTRIAZOLES AND DERIVATIVES, PLANT GROWTH REGULATORS | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1981-01-06 | — | — | US | claimed |