Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SLC11A2 | P49281 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11384779 | 0.72 | SMN1; SMN2 (0.38) | MAPTMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL23327143 | 0.69 | MAPK1 (0.53) | MAPTMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL4267728 | 0.64 | CYP3A4 (0.66) | MAPTMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL29788609 | 0.64 | CYP3A4 (0.66) | MAPTMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL5367920 | 0.64 | KMT2A (0.67) | MAPTMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL3233109 | 0.62 | ERN1 (0.47) | MAPTKMT2AGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL3028435 | 0.62 | KDM4E (0.47) | MAPTKMT2AALDH1A1LMNA | |
| SCHEMBL2093961 | 0.62 | KMT2A (0.44) | MAPTMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL11426116 | 0.62 | MYC (0.50) | MAPTMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL11375467 | 0.61 | KMT2A (0.51) | MAPTMEN1KMT2AGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4260776-A | PYRAZOLONE | BAYER AKTIENGESELLSCHAFT (DE) | 1981-04-07 | — | — | US | disclosed |