SCHEMBL1138098

SCHEMBL1138098

OC/C=C/CCl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4218879 1.00
SCHEMBL1138100 1.00
SCHEMBL205123 0.78
SCHEMBL229347 0.78
SCHEMBL160149 0.78
SCHEMBL41218 0.78
SCHEMBL41219 0.78
SCHEMBL258389 0.78
Methacrylic Acid SCHEMBL10647277 0.75 TDP1 (0.35)
SCHEMBL11613324 0.74 TDP1 (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114350331-B Strong-adsorption salt-resistant plugging agent based on nano-silica and water-based drilling fluid 西南石油大学 2023-01-31 CN claimed
CN-111650315-B Method for detecting alcohol metabolites of butadiene by using fluorescence derivatization-high performance liquid chromatography 上海大学 2022-11-18 CN claimed
CN-114350331-A Strong-adsorption salt-resistant plugging agent based on nano-silica and water-based drilling fluid 西南石油大学 2022-04-15 CN claimed
CN-111650315-A Method for detecting alcohol metabolites of butadiene by using fluorescence derivatization-high performance liquid chromatography 上海大学 2020-09-11 CN claimed
CN-114350331-B Strong-adsorption salt-resistant plugging agent based on nano-silica and water-based drilling fluid 西南石油大学 2023-01-31 CN disclosed
CN-111650315-B Method for detecting alcohol metabolites of butadiene by using fluorescence derivatization-high performance liquid chromatography 上海大学 2022-11-18 CN disclosed
CN-114350331-A Strong-adsorption salt-resistant plugging agent based on nano-silica and water-based drilling fluid 西南石油大学 2022-04-15 CN disclosed
CN-111650315-A Method for detecting alcohol metabolites of butadiene by using fluorescence derivatization-high performance liquid chromatography 上海大学 2020-09-11 CN disclosed
US-10752776-B2 Cyclic bio-renewable flame retardants INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2020-08-25 US disclosed
US-20200087515-A1 CYCLIC BIO-RENEWABLE FLAME RETARDANTS INTERNATIONAL BUSINESS MACHINES CORPORATION 2020-03-19 US disclosed
US-9505765-B2 4-alkoxy/aralkoxy-5-substituted-pyrrolopyrimidine compounds as TAK1 inhibitors in disease treatment CONFLUENCE LIFE SCIENCES INC. (US) 2016-11-29 US disclosed
US-20150203499-A1 4-ALKOXY/ARALKOXY-5-SUBSTITUTED-PYRROLOPYRIMIDINE COMPOUNDS AS TAK1 INHIBITORS IN DISEASE TREATMENT ACLARIS THERAPEUTICS, INC. 2015-07-23 US disclosed
WO-1997045473-A1 ABSOLUTE MOLECULAR WEIGHT POLYMERS AND METHODS FOR THEIR USE ALCON LABORATORIES, INC. (US) 1997-12-04 WO disclosed
WO-1997019092-A1 IMPROVED PROCESS FOR THE SYNTHESIS OF OLIGOMERIC COMPOUNDS ISIS PHARMACEUTICALS, INC. (US) 1997-05-29 WO disclosed
US-5547663-A Absolute molecular weight polymers and methods for their use ALCON LABORATORIES, INC. (US) 1996-08-20 US disclosed
US-4725628-A Process of making a crosslinked superabsorbent polyurethane foam KIMBERLY-CLARK CORPORATION (US) 1988-02-16 US disclosed
EP-0082804-B1 2-AMINO-1-(1,3-DIOXOLAN-4-YL)-ETHANOL COMPOUNDS, THEIR PREPARATION AND USE FOR FURTHER TREATMENT SCHERING AKTIENGESELLSCHAFT (DE) 1987-08-12 EP disclosed
US-4570007-A 2-Amino-1-(1,2-dioxolan-4-yl)ethanol compounds, their preparation and use SHERING AKTIENGESELLSCHAFT (DE) 1986-02-11 US disclosed
EP-0082804-A1 2-Amino-1-(1,3-dioxolan-4-yl)-ethanol compounds, their preparation and use for further treatment SCHERING AKTIENGESELLSCHAFT (DE) 1983-06-29 EP disclosed
US-4265836-A BY GRIGNARD REAGENT AND 1,4-DICHLORO-Z-BUTENE INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1981-05-05 US disclosed